Relying upon the basic tenets of scientific modeling, an ansatz for the evaluation of proton affinity of molecules are evolved in terms of a four component model. The components of the model chosen are global descriptors like ionization energies, global softness, electronegativity and electrophilicity index. These akin quantum mechanical descriptors of atoms and molecules are linked with the ch...

There is also a growing consensus that evidence of teachers’ contributions to student learning should be a component of teacher evaluation systems, along with evidence about the quality of teachers’ practice. “Value Added Models” (VAMs) for looking at gains in student test scores from one year to the next are promoted as tools to accomplish this goal. Policy makers can benefit from research abo...

Bioremediation uses various microorganisms to detoxify or degrade various harmful substances in the nature, particularly soil and water. In the proposed work, five species of micro-organisms were used to analyse their impact on various physico-chemical parameters of water. In the first attempt the actual physico chemical parameters of the collected sample water were noted down (Fresh sample par...

Background: Many of the most common cancers, such as prostate and breast cancer are due to the presence of harmful agents and compounds in processed foods, including nitrite. In this research the physicochemical, antioxidant, and color properties of sodium nitrite-free sausages containing different concentrations of cochineal pigment alone or in combination with cumin essential oil were studied...

Climate change mitigation acts by reducing greenhouse gas emissions, and thus curbing, or even reversing, the increase in their atmospheric concentration. This reduces the associated anthropogenic radiative forcing, and hence the size of the warming. Because of the inertia and internal variability affecting the climate system and the global carbon cycle, it is unlikely that a reduction in warmi...

In 1999, Medicare implemented a resource-based relative value unit (RVU) system for physician practice expense payments, and increased the number of services for which practice expense payments differ by site. Using 1998-2004 data, we examined RVU growth and decomposed that growth into resource-based RVUs, site of service, and service quantity and mix. We found that the number services with sit...

Proteochemometrics is a technology for the study of molecular recognition based on chemometric techniques. Here we applied it to analyse the amino acids and amino acid physico-chemical properties that are involved in antibodies' recognition of peptide antigens. To this end, we used a study system comprised by a diverse single chain antibody library derived from the murine mAb anti-p24 (HIV-1) a...

The effect of target molecule depletion from the supernatant solution is incorporated into a physico-chemical model of hybridisation on oligonucleotide microarrays. Two possible regimes are identified: local depletion, in which depletion by a given probe feature only affects that particular probe, and global depletion, in which all features responding to a given target species are affected. Exa...