نتایج جستجو برای: optimal dosage

تعداد نتایج: 465100  

Journal: :Science 2010
Murat Acar Bernardo F Pando Frances H Arnold Michael B Elowitz Alexander van Oudenaarden

Coping with variations in network dosage is crucial for maintaining optimal function in gene networks. We explored how network structure facilitates network-level dosage compensation. By using the yeast galactose network as a model, we combinatorially deleted one of the two copies of its four regulatory genes and found that network activity was robust to the change in network dosage. A mathemat...

Journal: :Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 1989

Journal: :Annals OR 2010
Miao He Lei Zhao Warren B. Powell

In the controlled ovarian hyperstimulation (COH) cycle of the in vitro fertilizationembryo transfer (IVF-ET) therapy, the clinicians observe the patients’ responses to gonadotropin dosages through closely monitoring their physiological states, to balance the trade-off between pregnancy rate and ovarian hyperstimulation syndrome (OHSS) risk. In this paper, we model the clinical practice in the C...

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