BACKGROUND To report a case of bilateral optic disc oedema and associated optic neuropathy in the setting of FOLFOX chemotherapy. CASE PRESENTATION A case of a 57-year-old male being treated with FOLFOX chemotherapy for stage 3B colorectal cancer, who developed bilateral optic disc oedema and associated left sided optic neuropathy is described. The patient presented following cycles 7, 8 and ...

PURPOSE The purpose of this study is to identify risk factors for severe thyroid-associated orbitopathy (TAO) and compressive optic neuropathy in Korean patients. METHODS This study was a retrospective comparative case series. All TAO patients who were first seen at our institution between 2005 and 2009 and who had follow-up periods of at least 6 months were included. Patients were divided in...

BACKGROUND AND PURPOSE MR imaging characteristics of optic neuropathy caused by cat scratch disease have not yet been described; this lack of information may result in incorrect diagnosis and may contribute to initiation of inappropriate therapy. Our study was based on the hypothesis that cat scratch disease-related optic neuropathy has distinct MR imaging features compared with those of other ...

Inherited disorders of the optic nerve significantly impact vision in children and adults. The optic nerve disorders most commonly encountered clinically are glaucoma and primary optic neuropathy including Leber's hereditary optic neuropathy (LHON) and autosomal dominant or Kjer's optic atrophy. Current knowledge of the genetics of optic neuropathy and glaucoma makes it possible to test for mut...

BACKGROUND Optic neuropathy is a rare manifestation of systemic lupus erythematosus (SLE). In a previous series most patients with optic neuropathy in association with SLE had a final visual acuity of 20/200 or less despite corticosteroid therapy. METHODS Three patients (five affected eyes) with severe retrobulbar optic neuropathy in association with SLE were treated promptly with intravenous...

Optic neuropathy is a frequent cause of vision loss encountered by ophthalmologist. The diagnosis is made on clinical grounds. The history often points to the possible etiology of the optic neuropathy. A rapid onset is typical of demyelinating, inflammatory, ischemic and traumatic causes. A gradual course points to compressive, toxic/nutritional and hereditary causes. The classic clinical signs...

Leber's Hereditary Optic Neuropathy is a rare disease caused by mutation in the mitochondrial DNA. It appears most often young men, leading to profound, permanent loss of vision short time. There no specific treatment for this condition.Idebenone medicine that administered patients with hereditary optic neuropathy improves or stops deterioration vision. Increasing number people during therapy a...

Visual loss is a traumatic occurrence that has been reported after prone spine surgical procedures performed under general anesthesia. The most common cause of postoperative visual loss is ischemic optic neuropathy. Although the incidence of postoperative visual loss is rare, this devastating injury has been reported more frequently. Several factors increase the risk for the development of isch...

Background: Diabetes, low nighttime blood pressure, and nonarteritic ischemic optic neuropathy may be associated. Not too many studies present whether this relationship applies to patients. Objective: Diabetes mellitus, pressure at night, were studied in a group of individuals. Methods: The ophthalmology clinic will conduct cross-sectional research on patients with from March 2019 December 2021...

glaucoma is a major cause of worldwide irreversible blindness. the central role of raised intraocular pressure (iop) is being questioned as many patients continue to demonstrate a clinically downhill course despite initial control of iop. the latest concept of recognizing glaucoma as a multifactorial, progressive, neurodegenerative disease of retinal ganglion cells (rgcss) associated with chara...