There are a few studies with conflicting results on the effects of opioids on the functioning of immune system. This study was performed to investigate the in vitro production of interferon-gamma and interleukin-10 after antigenic stimulation of cells using whole blood from opioid addicts. Blood samples were taken from 20 chronically opioid-addicted persons, who voluntarily enrolled for detoxif...

BACKGROUND Given the paucity of data on possible testis changes in opioid dependents, we sought to compare the testis volumes between a group of opium dependents and a group of healthy controls. OBJECTIVE Comparison of testis volume between opium dependents and healthy controls. MATERIALS AND METHODS This case-control study recruited 100 men with opium dependency (cases) and 100 healthy men...

BACKGROUND It has been demonstrated that chronic opium abusers have lower thresholds for pain. Spinal anesthesia is a common procedure in anesthesia, which is performed through administration of drugs (usually local anesthetics) in the intrathecal space, to produce temporary pain relief. The aim of this study was to determine whether chronic opium abuse could have any possible effect on the dur...

Over the course of human history, it has been common to use plants for medicinal purposes, such as for providing relief from particular maladies and self-medication. Opium represents one longstanding remedy that has been used to address a range of medical conditions, alleviating discomfort often in ways that have proven pleasurable. Opium is a combination of compounds obtained from the mature f...

Background: Opioid use disorder is a major concern to public health, and opioid maintenance treatment onmethadone or buprenorphine is a widely used approach. On the other hand, in recent years, there has beenmore regards for the use of opium tincture for detoxification and maintenance treatment of opioiddependence in certain parts...

Background: Lead poisoning is an issue of concern in developing countries and high levels of lead in blood could be resulted following occupational and environmental exposures. Several reports have raised concerns on the increasing prevalence of lead intoxication among opioid addicts. This study investigated the clinical manifestations and demographic data of subjects who were ...

BACKGROUND Opium abuse significantly affects the nutritional status of users and frequently leads to undernourishment. Methadone maintenance therapy has been used as one of the possible ways to prevent of infection diseases such as HIV and hepatitis B and C and improve the quality of life in opioid-dependent patients. OBJECTIVES The aim of this study was to assess the anthropometric and socio...

objectives the aim of this study was to evaluate the biological effects of opium on the number of peripheral blood cells and red blood cells (rbcs) indices in diabetic rats. materials and methods peripheral blood samples were collected from diabetic, opium-addicted, diabetic opium-addicted and normal male and female rats and hematological parameters were measured. results the mean number of whi...

For centuries the world has appreciated the potent analgesic qualities and adverse effects/addictive qualities of opioids. Evidence of potential poppy plant use (preserved remains of cultivated poppy seeds and pods) may date back to the fourth millennium BC (2). Opium was proposed as a remedy for multiple ailments in 1552 BC in the Ebers papyrus. Drug use in ancient central Asia is evidenced by...

background: opium is a new source of lead and considered as a cause of lead poisoning. as anemia and lead poisoning affect growth and behavior negatively, their timely prevention, diagnosis, and treatment are essential. the aim of thi study is evaluation of the prevalence of anemia, iron deficiency anemia, and lead poisoning in children with opioid toxicity. materials and methods: in this cross...