نتایج جستجو برای: opioid addiction

تعداد نتایج: 52416  

2014
Amin Dinarvand Ali Goodarzi Nasim Vousooghi Mehrdad Hashemi Rasoul Dinarvand Fahimeh Ostadzadeh Ahad Khoshzaban Mohammad-Reza Zarrindast

INTRODUCTION Association between single-nucleotide polymorphisms (SNPs) in mu opioid receptor gene and drug addiction has been shown in various studies. Here, we have evaluated the existence of polymorphisms in exon 3 of this gene in Iranian population and investigated the possible association between these mutations and opioid addiction. METHODS 79 opioid-dependent subjects (55 males, 24 fem...

Journal: :Neuroanatomy and behaviour 2021

Opioid abuse is a growing global problem. Current therapies for opioid target withdrawal symptoms and have several adverse side effects. There are no treatments to address opioid-induced neural adaptations associated with addiction. Preclinical research demonstrates interactions between the endogenous cannabinoid systems, suggesting that cannabinoids may be used treat addiction dependence. The ...

Journal: :Canadian family physician Medecin de famille canadien 2011
Meldon Kahan Lynn Wilson Angela Mailis-Gagnon Anita Srivastava

OBJECTIVE To provide family physicians with a practical clinical summary of opioid prescribing for specific populations based on recommendations from the Canadian Guideline for Safe and Effective Use of Opioids for Chronic Non-Cancer Pain. QUALITY OF EVIDENCE Researchers for the guideline conducted a systematic review of the literature, focusing on reviews of the effectiveness and safety of o...

Journal: :Journal of the National Medical Association 2012
Jean Bonhomme Ruth S Shim Richard Gooden Dawn Tyus George Rust

Opioid abuse and addiction have increased in frequency in the United States over the past 20 years. In 2009, an estimated 5.3 million persons used opioid medications nonmedically within the past month, 200000 used heroin, and approximately 9.6% of African Americans used an illicit drug. Racial and ethnic minorities experience disparities in availability and access to mental health care, includi...

2014
Zhang Boyuan Chen Yang Cheng Ke Shen Xueyong Liu Sheng

This review systematically assessed the clinical evidence for and against acupuncture as a treatment for psychological symptoms associated with opioid addiction. The database was accessed from MEDLINE and China Knowledge Resource Integrated Database. We included all randomized clinical trials published in Chinese and English regardless of their controls. Meta-analysis was performed using the Re...

Journal: :Archives of internal medicine 2004
Mori J Krantz Philip S Mehler

Almost 3 million Americans have abused heroin. The most effective treatment for this concerning epidemic is opioid replacement therapy. Although, from a historical perspective, acceptance of this therapy has been slow, growing evidence supports its efficacy. There are 3 approved medications for opioid maintenance therapy: methadone hydrochloride, levomethadyl acetate, and buprenorphine hydrochl...

Journal: :The American journal of medicine 2013
Sarah Bowman Julie Eiserman Leo Beletsky Sharon Stancliff R Douglas Bruce

Addiction to prescription opioids is prevalent in primary care settings. Increasing prescription opioid use is largely responsible for a parallel increase in overdose nationally. Many patients most at risk for addiction and overdose come into regular contact with primary care providers. Lack of routine addiction screening results in missed treatment opportunities in this setting. We reviewed th...

Journal: :The American journal on addictions 2003
Herbert D Kleber

Given the difficulty of achieving sustained recovery, pharmacotherapy of opioid and cocaine addiction is more effective when combined with behavioral and psychosocial approaches. Effective pharmacotherapies for opioid dependence and withdrawal include methadone, L-alpha acetylmethadol (LAAM), naltrexone, buprenorphine, and clonidine. Treatment of cocaine addiction includes anti-craving agents, ...

Journal: :Substance use & misuse 2005
Penelope P Ziegler

Persons experiencing pain, whether acute or chronic, seek and deserve relief from their discomfort and loss of function. However, opioid analgesics have the capacity to induce tolerance, physical dependence, and addiction. Furthermore, persons with a history of opioid use disorders or other substance misuse problems are at "high risk" when they acquire painful conditions requiring aggressive tr...

Introduction: X chromosome inactivation (XCI) is a process during which one of the two X chromosomes in female human is silenced leading to equal gene expression with males who have only one X chromosome. Here we have investigated XCI ratio in females with opioid addiction to see whether XCI skewness in women could be a risk factor for opioid addiction. Methods: 30 adult females meeting DS...

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