introduction: there is a limited number of case reports published in the past decade confirming the radio-iodine presence in the tear. these observations as well as reported cases of salivary and lacrimal gland dysfunction after radioiodine therapy stimulated investigators to clarify whether lacrimal gland function can be affected post-radioiodine therapy. hence we planned a historical cohort s...

PURPOSE The Schirmer's test is commonly used in the clinic for the diagnosis of dry eye disease by measuring tear volume. This report describes a procedure which can be used to recover tears from the Schirmer strip for the measurement of multiple tear cytokines as well as matrix metalloproteinases (MMPs) by Luminex technology. METHODS Cytokine and MMP recovery was determined by using spiked S...

the aim of this study was to evaluate the efficacy of a hyaluronic acid containing eye drop in ameliorating ocular surface pathology and discomfort in canine keratoconjunctivitis sicca (kcs). twenty five dogs with kcs treated with a topical carbomer (ca)-based tear replacement gel were moved to treatment with a hyaluronic acid (ha)-containing tear replacement eye drop. dogs were subject to a fu...

Purpose. To use optical coherence tomography (OCT) to evaluate the effect of punctal occlusion on tear meniscus volume in dry eye patients. Methods. Occlusion of both upper and lower puncta with collagen plugs was performed on one eye each in 20 dry eye patients and 20 normal subjects. The upper and lower tear menisci were imaged simultaneously by real-time OCT before punctal occlusion and on d...

The purpose of this comparative cross-sectional study was to investigate the use of standardized clinical tests for dry eye in pediatric patients with active and quiet vernal keratoconjunctivitis (VKC) and to compare them with healthy children. We recruited 35 active VKC, 35 inactive VKC, and 70 age-matched control healthy subjects. Each child underwent a complete eye examination, including vis...

AIM: To evaluate the efficacy and tolerability of administering a combined therapy in patients with dry eye syndrome (DES) associated laryngopharyngeal reflux (LPR). METHODS: The study was retrospective, open, observational, conducted real-life setting. Patients had pathological symptom assessment (SANDE) index (RSI) at baseline. were re-assessed after 1mo end treatment. treatment consisted thr...

This study was designed to evaluate efficacy of a natural eye drop made of Plantago ovata mucilage versus placebo to improve dry eye symptoms. In a Randomized, double-masked, placebo-controlled clinical trial, sixty dry eye patients with ocular symptom and total OSDI score≥12 were randomly assigned to receive either a natural ophthalmic drop, made of Plantago ovata mucilage or placebo 4 times a...

Purpose. To evaluate the relationship between corneal and conjunctival epithelium thickness and ocular surface clinical tests in dry eye disease (DED) patients. Patients and Methods. Fifty-four patients with DED and 32 control subjects were included. Each patient underwent an ocular surface evaluation using the ocular surface disease index (OSDI), tear film break-up time (TBUT), corneal and con...

This study was designed to evaluate efficacy of a natural eye drop made of Plantago ovata mucilage versus placebo to improve dry eye symptoms. In a Randomized, double-masked, placebo-controlled clinical trial, sixty dry eye patients with ocular symptom and total OSDI score≥12 were randomly assigned to receive either a natural ophthalmic drop, made of Plantago ovata mucilage or placebo 4 times a...

OBJECTIVE The aim of this study was to evaluate the tear clearance in patients with dry eye syndrome using quantitative lacrimal scintigraphy. MATERIALS AND METHODS We investigated 21 patients (42 eyes; 18 women, 3 men; mean age, 63.19 +/- 13.33 years) with dry eye syndrome. Additionally, for the sake of comparison, 12 normal subjects of the same age group (24 eyes; 10 women, 2 men; mean age,...