Nucleocytoplasmic coupling is mediated by outer nuclear membrane (ONM) nesprin proteins and inner nuclear membrane Sun proteins. Interactions spanning the perinuclear space create nesprin-Sun complexes connecting the cytoskeleton to nuclear components. A search for proteins displaying a conserved C-terminal sequence present in nesprins 1-3 identified nesprin 4 (Nesp4), a new member of this fami...

A new theory on designing electromagnetic/optical devices is proposed, namely, an optical surface transformation (OST). One arbitrary surface can establish the corresponding relationship with another surface entirely optically with an optic-null medium (ONM), (i.e. the electromagnetic wave propagates from one surface to its equivalent surface without any phase delay). Many novel optical devices...

The nucleus in eukaryotic cells can move within the cytoplasm, and its position is crucial for many cellular events, including migration and differentiation. Nuclear anchorage and movement can be achieved through association of outer nuclear membrane (ONM) proteins with the three cytoskeletal systems. Two decades ago studies described C. elegans mutants with defects in such events, but only rec...

UNLABELLED We report three patients who developed symptoms and signs of ocular neuromyotonia (ONM) 3-6 months after receiving gamma knife radiosurgery (GKS) for functioning pituitary tumours. All three patients were complex, requiring multi-modality therapy and all had received prior external irradiation to the sellar region. Although direct causality cannot be attributed, the timing of the dev...

Z. Takáč in [16] introduced the aggregation operators on any subalgebra of M (set of all fuzzy membership degrees of the type-2 fuzzy sets, that is, the functions from [0,1] to [0,1]). Furthermore, he applied the Zadeh’s extension principle (see [24]) to obtain in [16, 17] a set of aggregation operators on L* (the strongly normal and convex functions of M). In this paper, we introduce the aggre...

The paper assesses the performances of the urban local bodies in the state of Karnataka in India.We use non parametric Data Envelopment Analysis as a tool to measure technical efficiencies of the ULBs. If we compare the services in a particular size class of city with the norms we find that in the smallest size class it is water supply which has the minimum shortfall from norms, in the medium s...

Correspondence to Daniel A. Starr: [email protected] Abbreviations used in this paper: DIC, differential interference contrast; fps, frame per second; INM, inner nuclear membrane; KASH, Klarsicht, ANC-1, and Syne homology; LINC, linker of nucleoskeleton and cytoskeleton; NE, nuclear envelope; ONM, outer nuclear membrane; PNS, perinuclear space; SUN, Sad1p and UNC-84; TEM, transmission EM. Int...