conclusions pressure support ventilation, but not spontaneous breathing, induces a significant redistribution of ventilation towards the ventral region. the sensitivity of the support trigger appears to influence the distribution of ventilation only during the early phase of inspiration. background in supine position, pressure support ventilation causes a redistribution of ventilation towards t...

BACKGROUND One-lung ventilation during thoracic surgery frequently disturbs normal systemic oxygenation. However, the effect of anesthetics on arterial oxygenation during one-lung ventilation has not been well established in human study. In this clinical trial, we investigated whether a difference between desflurane-remifentanil and propofol-remifentanil anesthesia can be observed with regard t...

BACKGROUND Pressure-controlled ventilation (PCV) has been suggested to reduce peak airway pressure (P(peak)) and intrapulmonary shunt during one-lung ventilation (OLV) when compared with volume-controlled ventilation (VCV). At the same tidal volume (V(T)), the apparent difference in P(peak) is mainly related to the presence of a double-lumen tracheal tube. We tested the hypothesis that the decr...

Noninvasive ventilation has been available for over 100 years. In the past 25 years, relatively lightweight, portable ventilators and comfortable interfaces have become available that have allowed for full-time noninvasive ventilation. In motivated individuals who have access to centers with expertise in nocturnal and diurnal ventilation, continuous noninvasive ventilation is quite feasible. Th...

I read with great interest the article by Raman et al 1 in a recent issue of CHEST (February 2015) that evaluated the pressure tolerance of esophagectomy anastomosis ex vivo and in vivo in a pig model in comparison with esophageal pressure during noninvasive positivepressure ventilation (NPPV). Th e authors showed that anastomosis can tolerate higher pressures than those transmitted to the esop...

One lung ventilation (OLV) is required for surgical intervention in patients with lung cancer. One lung ventilation is needed for better exposure and maintenance of ventilation and oxygenation. One lung ventilation for lung surgeries are associated with changes in respiratory mechanics. Also, OLV may lead to lung injury to both the ventilated lung and the collapsed lung and is associated with h...

BACKGROUND It is known that hypoxic pulmonary vasoconstriction increases as a result of intermittent regional hypoxic challenges. The aim of this study was to compare the effects of sevoflurane and propofol on oxygenation and shunt fraction during one-lung ventilation in a novel model of hypoxic preconditioning before one-lung ventilation. METHODS Sixteen Wistar-albino rats were anesthetized ...