Background: Esketamine and ketamine have been shown to produce rapid antidepressant action in patients with treatmentresistant depression (TRD). The aim of the current study was to assess the efficacy, safety and dose response of intranasal esketamine in patients with TRD. Methods: This was a 2-Panel, doubly-randomized, double-blind, placebo-controlled, multicenter study. Panel A was conducted ...

abstract the increasing of yield per unit area is usually achievable by improving the soil fertility level through using (chemical) fertilizers. the purpose of the present research was to evaluate the 6 extraction methods including olsen, morgan, ammonium bicarbonate-dtpa, colwel, bray and mehlich 3 in order to specify a suitable extractant(s) for estimating available phosphorus through using 2...

Abstract Managing soils for improved agricultural production requires information on soil fertility status. Our objective was to map better management in Ethiopia and determine their spatial correlation at a separation distance of 29 m. We collected 82 samples (0–20 cm depth) 560 ha land determined pH, Olsen extractable phosphorus (Olsen‐P), organic carbon (OC). then interpolated between sample...

Recognition of the public health and financial problems involved in the increasing use of pharmaceutical products is of major importance to-day (WHO, 1971). A deeper knowledge of the extent and development of drug consumption is necessary to evaluate the significance of these problems. It is possible to obtain such knowledge in relatively few countries (Engel and Siderius, 1968; NMD, 1972). The...