OBJECTIVE To evaluate the changes in cerebral blood flow during awake off-pump coronary artery bypass grafting and compare with the changes during off-pump coronary artery bypass grafting under general anesthesia, using continuous monitoring of regional cerebral oxygen saturation. METHODS The study population comprised 3 groups of patients who had undergone off-pump coronary artery bypass gra...

INTRODUCTION- Cardiovascular disease has emerged as a major health burden worldwide with coronary artery disease [CAD] causing highest mortality and morbidity. Coronary revascularization is the preferred treatment for patients with multivessel CAD. Based on the application of cardiopulmonary bypass [CPB], Coronary revascularization can be on-pump [OPCAB] or off-pump [CABG].The CPB is known to h...

OBJECTIVE To compare the clinical, angiographic, neurocognitive, and quality of life outcomes of off-pump coronary artery bypass surgery with conventional coronary artery bypass grafting surgery using cardiopulmonary bypass. DESIGN Randomised controlled clinical trial. SETTING Tertiary cardiothoracic centre in Middlesex, England. PARTICIPANTS 168 patients (27 women) requiring primary isol...

Coronary artery bypass grafting: on-pump or off-pump? With a growing evidence base surrounding off-pump cardiac surgery, Confluence spoke to Professor Massimo G Lemma, Luigi Sacco University General Hospital, Milan, Italy about how the results of his most recent study investigating on-pump versus off-pump coronary artery bypass surgery in high-risk patients might impact clinical practice. m g L...

OBJECTIVE Coronary artery bypass grafting is currently the best treatment for dialysis patients with multivessel coronary artery involvement. Vasoplegic syndrome of inflammatory etiology constitutes an important postoperative complication, with highly negative impact on prognosis. Considering that these patients have an intrinsic inflammatory response exacerbation, our goal was to evaluate the ...

The authors undertook a meta-analysis of 37 randomized trials (3369 patients) of off-pump coronary artery bypass surgery versus conventional coronary artery bypass surgery. No significant differences were found for 30-day mortality (odds ratio [OR], 1.02; 95% confidence interval [CI], 0.58-1.80), myocardial infarction (OR, 0.77; 95%CI, 0.48-1.26), stroke (OR, 0.68; 95%CI, 0.33-1.40), renal dysf...

Introduction: Heart failure is a major hazard for public health. Despite recent advance in medical therapy, there is not enough information on the outcome of off-pump coronary artery bypass (OPCAB) and medical therapy on the patients with severe ventricular dysfunction and triple-vessel (CAD). This study aimed to compare treatment outcomes and mortality rate in patients undergoing off-pump coro...

BACKGROUND Off-pump coronary artery bypass grafting has been accused of possibly compromising graft patency. Sixteen slice computed tomography has shown good diagnostic accuracy in the assessment of coronary bypass graft patency when compared with conventional coronary artery angiography and is less invasive. The study hypothesis is that coronary artery bypass grafting (CABG) performed without ...

conclusions our study showed superiority of off-pump cabg regarding lvef, rvef and valves regurgitations. future studies with prospective structure, accurate randomization, longer follow up duration, and larger sample size are needed. results one hundred eighteen patients with the mean age of 59.47 ± 9.68 years were included (81 male and 37 female). on-pump cabg was done on 84 patients and off-...

OBJECTIVES To review the evolution of off-pump coronary artery bypass surgery with particular reference to the anaesthetic and perioperative implications. FINDINGS After review of the literature regarding coronary artery bypass grafting, the adverse effects of cardiopulmonary bypass on the various systems are discussed The development and the present status of off-pump coronary artery bypass ...