BACKGROUND Increased serum levels of angiotensin converting enzyme and lysozyme are considered as inflammatory markers for diagnosis of sarcoidosis which is an autoimmune inflammatory disease. The purpose of this study is to evaluate the significance of differences in serum angiotensin converting enzyme and lysozyme levels of patients with ocular involvement of other autoimmune inflammatory and...

A 42-year-old man with unusual ocular involvement complicating secondary syphilis is demonstrated. The patient was admitted to the dermatological department because of erythematous plaques on the hands and soles. Prior to admission these lesions were misdiagnosed as erythema multiforme and treated with systemic corticosteroids. Besides the skin lesions the patient complained of headache and blu...

During a 6-month period in 2010, 2 patients with uveitis were examined at our department and diagnosed with ocular syphilis. They initially presented with symptoms and signs resembling Harada's disease and Behçet's disease and were therefore treated with systemic steroids with suboptimal responses. When laboratory workup revealed neurosyphilis, they were given a course of intravenous penicillin...

Diagnosis and treatment of syphilis are challenging because of the condition's diverse clinical symptoms, histopathological variance, and the lack of definite tests for treatment follow-up. We report a case of secondary pustular-ulcerative malignant syphilis with ocular involvement in a human immunodeficiency virus-infected patient. It was striking to find that ulcerative lesions can be highly ...

Background: Detection and treatment of syphilitic ocular disease without a known history syphilis is often difficult due to its varied presentations. Early diagnosis are the key reducing risk permanent vision loss, particularly with optic nerve retinal manifestations. Case Report: This case report describes 44 year-old male who was diagnosed neurosyphilis through his work-up for unilateral neur...

PURPOSE This study was conducted to determine the incidence of luetic uveitis in the last seven years at our uveitis center and to describe the characteristics and the role of uveitis in the diagnosis of syphilitic infection with or without unknown HIV infection. METHODS We retrospectively reviewed syphilitic uveitis in patients observed at our center between 2004 and 2010. The diagnosis was ...