The role of dietary fibres in colon carcinogenesis is controversial. To elucidate the mechanisms by which different dietary fibre sources may affect colonic tumour development, we studied the effects of diets enriched with cereal brans or inulin on protein kinase C (PKC) activity and isozyme expression in rat colon. Male Wistar rats (twelve per group) were fed one of the following AIN-93G-based...

INTRODUCTION Oats are high in soluble fibers and effective in reducing the risk of cardiovascular diseases (CVD). We assessed the effects of beta-glucan from oat bran on serum nitric oxide (NO) endothelial function in patients with hypercholesterolemia. METHOD Sixty hypercholesterolemic patients were randomly divided to receive an experimental bread rich in beta-glucan from oat bran (interven...

The aim of this study was to evaluate the effect of oat bran supplementation on time to exhaustion, glycogen stores and cytokines in rats submitted to training. The animals were divided into 3 groups: sedentary control group (C), an exercise group that received a control chow (EX) and an exercise group that received a chow supplemented with oat bran (EX-O). Exercised groups were submitted to an...

Oat β-glucan was purified from oat bran and its effects on running performance and related biochemical parameters were investigated. Four-week-old male Sparsgue-Dawley rats, fed with/without oat β-glucan (312.5 mg kg(-1) d(-1)) for 7 weeks, were subjected to run on a treadmill system to make them exhausted. All rats were immediately sacrificed after prolonged exercise, and the major metabolic s...

Nutrients not absorbed in the small bowel will form substrates for microbial growth in the colon which may have implication for the development of colon cancer. The aim of the present study was to investigate whether fibre-rich oat and barley diets increase the excretion of energy-supplying nutrients from the small bowel compared with a low-fibre wheat diet, and whether a possible increase coul...

In vitro bile acid binding without the use of labeled isotopes is an economical method for screening various foods and food fractions to evaluate their healthful potential before initiating timeand costintensive animal and human studies. Bile acids are needed for fat absorption, and high-fat diets are implicated in obesity, as well as raising plasma cholesterol. Bound bile acids are excreted an...

Despite the high levels of polyphenolic phytochemicals in grain sorghum and its position as a major food staple, there has been a lack of research on its effects on both animal and human health and disease prevention. These phenolic compounds, mainly located in the bran fraction, result in the plant having substantial antioxidant properties. This study examined the effect of ethanol extracts of...

Oat bran has gained significant attention among cereal brans owing to its comparatively higher presence of dietary fibers and phytochemicals. The objective the current research is personify nutritional functional aspects oat after yeast-induced (Saccharomyces cerevisiae) fermentation. For this purpose, a comparative study raw fermented was conducted investigate profile, antioxidant activity cha...