Echinacoside (ECH) is one of the major active phenylethanoid glycosides (PEGs) in famous traditional Chinese medicine, Herba Cistanches. Although it has various bioactivities, such as antioxidation, neuroprotection, and hepatoprotection, knowledge about its metabolic fate is scant. In the present study, eight phase II metabolites, 3,4 -O-dimethyl-ECH-3 -O-beta-d-glucuronide (M1); 4,4 -O-dimethy...

In the title compound, C(7)H(11)N(2) (+)·C(7)H(7)O(3)S(-), the cation is protonated at the N atom of the heterocyclic ring. The dimethyl-amino group lies close to the pyridinium ring plane with a dihedral angle between the pyridinium and the dimethyl-amine CNC planes of 3.82 (17)°. The N-C bond linking the dimethyl-amino substituent to the pyridinium ring is characteristically short [1.3360 (19...

In the title polymeric complex, [Zn(2)(C(6)H(2)O(4)S)(2)(C(4)H(9)NO)(2)](n), each carboxyl-ate group of the thio-phene-2,5-dicarboxyl-ate dianion bridges a pair of inversion-related dimethyl-acetamide-coordinated Zn(II) atoms, generating a layer motif parallel to (101). The Zn(II) atom shows a distorted square-pyramidal coordination; the apical site is occupied by the O atom of the dimethyl-ace...

In the title compound, [Sn(C(2)H(2)O(2)S)(2)(C(2)H(6)OS)(2)], the mercaptoacetato ligands chelate to Sn(IV) through S and one O atoms. The metal centre is also coordinated by two dimethyl sulfoxide (DMSO) ligands through the O atom, leading to an overall distorted octahedral coordination environment for the Sn(IV) atom. The mol-ecular adduct lies on a twofold rotation axis.

In the title compound, C(15)H(17)NO, the 2,3-dimethyl-phenyl group is disordered over two sites with an occupancy ratio of 0.869 (3):0.131 (3). The major and minor components of the 2,3-dimethyl-anilino group are planar, with r.m.s. deviations of 0.0214 and 0.0303 Å, respectively, and are oriented at a dihedral angle of 2.6 (6)°. The phenyl-methanol-benzene ring is oriented at dihedral angles o...

In the title cocrystal, [Ni(C(11)H(10)N(3)O(2))(2)]·[Ni(NCS)(2)(C(11)H(11)N(3)O(2))(H(2)O)], both Ni(II) ions are in disorted octa-hedral coordination environments. One Ni(II) ion is coordinated by four N atoms and two O atoms from two tridentate 6-(3,5-dimethyl-1H-pyrazol-1-yl)picolinate (DPP) ligands, while the other Ni(II) ion is coordinated by a tridentate 6-((3,5-dimethyl-1H-pyrazol-1-yl))...

In the crystal of the title salt, 2C(2)H(8)N(+)·C(6)H(4)O(8)S(2) (2-), the anion lies on a center of inversion. The dimethyl-ammonium cation forms one N-H⋯O hydrogen bond and another bifurcated N-H⋯O hydrogen bond. The hy-droxy group links with the sulfonyl group via an inter-molecular O-H⋯O hydrogen bond. These N-H⋯O and O-H⋯O hydrogen bonds generate a three-dimensional network.

The title compound, 0.759C(19)H(21)ClN(2)O(2)S·0.241C(19)H(21)ClN(2)O(2)S, was synthesized by aryl-sulfonyl-ation of 2-n-butyl-5-chloro-1H-benzimidazole in the presence of triethyl-amine. The crystal structure is composed of two mol-ecules, 2-n-butyl-6-chloro-1-(2,4-dimethylphenyl-sulfon-yl)-1H-benzimidazole and 1-(2,4-dimethylphenyl-sulfon-yl)-2-n-butyl-5-chloro-1H-benz-imidazole, in the refin...

The complete mol-ecule of the title compound, [Cd(C(10)H(9)N(4)O(2)S)(2)(C(2)H(6)OS)(2)], is completed by the application of a twofold rotation axis. The Cd(II) atom is six coordinated by two bidentate sulfadiazinate anions and two dimethyl-sulfoxide mol-ecules. The resulting N(4)O(2) donor set displays a distorted trigonal-prismatic coordination geometry. The S atom and methyl groups of dimeth...

In the mol-ecule of deferasirox dimethyl-formamide solvate, C(21)H(15)N(3)O(4)·C(3)H(7)NO, the central 1,2,4-triazole ring is tilted with respect to the benzoic acid and one of the 2-hy-droxy-phenyl units but coplanar with the other 2-hy-droxy-phenyl group, as indicated by the dihedral angles of 33.69 (9), 72.57 (8) and 5.18 (9)°, respectively. Intra-molecular O-H⋯N hydrogen bonds generate an S...