The interaction between the human body and nutrition is an extremely complex process involving multi-organ physiology with molecular mechanisms on all levels of regulation (genes, gene expression, proteins, metabolites). Only with the recent technology push have nutritional scientists been able to address this complexity. Both the challenges and promises that are offered by the merge of 'biomic...

The link between genome instability and adverse health outcomes during the various stages of life, such as infertility, fetal development and cancer, is briefly reviewed against a background of evidence indicating that genome instability, in the absence of overt exposure to genotoxins, is itself a sensitive marker of nutritional deficiency. The latter is illustrated with cross-sectional and die...

Now that we have entered the postgenomic era, the association between the potential protective role of nutrients and periodontal diseases is well established. It is likely to know that interactions between the genotype and diet are important in determining periodontal disease risk. A change in dietary pattern represents a promising approach in reducing the risk of aging by modulating gene expre...

Ransom L. Baldwin VI, Robert W. Li, Cong-jun Li, Jennifer M. Thomson, and Brian J. Bequette Bovine Functional Genomics Laboratory, Animal and Natural Resources Institute, United States Department of Agriculture-Agricultural Research Service, Beltsville, Maryland; Department of Agriculture, Food and Nutritional Science, University of Alberta, Edmonton, Canada; and Department of Animal & Avian Sc...

Nutritional Genomics studies diet-gene-disease interactions and aims to promote health and disease prevention. It is based on the idea that everything ingested into a person’s body affects the genome of the individual and, therefore, both genes and nutrients modify the same metabolic processes. This paper presents an application of clustering and interpretation over real heterogeneous data comi...

Early 2014, the US Academy of Nutrition and Dietetics wrote in its position statement that “nutritional genomics provides insight into how diet and genotype interactions affect phenotype”[1] Nutrients can dictate phenotypic expression of an individual’s genotype by influencing the processes of gene transcription and protranscriptional processes (including translation). More important, the US Ac...

Background: DNA amplification method has been developed for identifying and discriminating Salmonella serovars, using specific primers at the genus and serovar levels and to identify the S. Enteritidis, S. Dublin, S. Gallinarum and S. Pullorum. Objectives: This study was conducted for molecular identification and discrimination among some important Salmonella serovars. Methods: Fifty isolates o...