In Alzheimer Disease (AD), dementia is due to cell loss and impaired synaptic function. The cell loss is mediated by increased apoptosis, predisposition to apoptosis, and impaired mitochondrial function. Previous studies demonstrated that the AD7c-NTP neuronal thread protein gene is over-expressed in AD beginning early in the course of disease, and that in AD, AD7c-NTP protein accumulation in n...

Inactivation of Bacillus amyloliquefaciens (BA) spores by non-thermal plasma (NTP) was investigated by studying inactivation kinetics and using attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FTIR). ATR-FTIR is a useful tool to probe the biochemical and structural changes of spores after NTP treatment in order to better manipulate and optimize the parameters for NTP pro...

In this work, the g-C 3 N 4 /V 2 C MXene composite catalyst was prepared by solvothermal method, and its denitration performance under synergistic plasma (NTP) investigated. The results showed that when mass ratio of V is 3%, V-CN-3-NTP as high 83.3%, which 1.2 2.1 times C-NTP -NTP systems alone. apparent morphology, phase structure, catalytic mechanism were studied SEM, TEM, XRD, FTIR, XPS, et...

Although the epidermal growth factor receptor (EGFR) is an established target in head-and-neck cancer (HNC), resistance to EGFR-targeted therapy mediated by various mechanisms has been reported. Therefore, a combination strategy to overcome resistance to EGFR mono-targeted therapy is clinically required. We have previously demonstrated that non-thermal atmospheric pressure plasma (NTP) induces ...

For decades, the Network Time Protocol (NTP) has been used to synchronize computer clocks over untrusted network paths. This work takes a new look at the security of NTP’s datagram protocol. We argue that NTP’s datagram protocol in RFC5905 is both underspecified and flawed. The NTP specifications do not sufficiently respect (1) the conflicting security requirements of different NTP modes, and (...

OBJECTIVE Comparative study of CSF levels of tau and AD7C-neuronal thread protein (NTP) in patients with AD and control subjects. BACKGROUND AD is characterized by neurofibrillary tangles composed of the abnormally hyperphosphorylated microtubule-associated protein tau. AD7C-NTP is a proposed AD marker expressed at early stages of neurofibrillary degeneration. METHODS Enzyme-linked immunoso...

PURPOSE To determine the effects of nonthermal plasma (NTP) induced by helium (He) alone or He plus oxygen (O₂) on the generation of reactive oxygen species (ROS) and cell death in anaplastic thyroid cancer cells. MATERIALS AND METHODS NTP was generated in He alone or He plus O₂ blowing through a nozzle by applying a high alternating current voltage to the discharge electrodes. Optical emissi...

A 437 The NIEHS Division of Extramural Research and Training (DERT), in collaboration with the National Toxicology Program (NTP), initiated a unique grants program in 1997 that funds investigatorinitiated research to provide data to aid in defining the mechanism of action of agents under study by the NTP. This program uses the NIH R03 Small Grant mechanism to encourage investigatorinitiated hyp...

OBJECTIVES/HYPOTHESIS Six nasal tip projection (NTP) ratios from Goode, Simons, Baum, Powell, and Crumley guide clinical and academic practice on quantifying NTP, but none have been empirically correlated with facial attractiveness. This study's objectives were to determine: 1) if there is a correlation between these ratios and facial attractiveness; and 2) which of the six ratios has the great...

Estimates were made of the proportion of chemicals that were carcinogenic, anticarcinogenic, or either in 397 long-term bioassays conducted by the National Toxicology Program (NTP). The estimates were obtained from the global pattern of p-values obtained from statistical tests applied to individual experiments. These tests accounted for multiple comparisons using a randomization procedure and w...