objective one of the prominent microorganisms in several reports of nosocomial infections is staphylococcus aureus (s. aureus) which is carried by several health care workers (hcw) many times throughout the day. the present investigation was conducted to assess the nasal and hand carriage rate of s. aureus amongst medical personnel of loghman hakim hospital's toxicological intensive care unit (...

Methicillin-resistant Staphylococcus aureus (MRSA) first came to the attention of health care providers as a nosocomial pathogen.1 More recently, MSRA has emerged as an important community-acquired pathogen2 and has been a cause of infection in men who have sex with men (MSM)3,4 and in persons with HIV-1 infection.5-7 Other reports include clusters of MRSA infection in prison inmates,8 military...

A rapid emergence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection (from 26.3% in 1986 to 77% in 2001) was found. The susceptibility of 200 nonduplicate blood isolates of MRSA and 100 MRSA isolates causing refractory bacteremia to 22 antimicrobial agents disclosed that glycopeptides, quinupristin-dalfopristin, and linezolid remained the most active agents.

background: methicillin resistant staphylococcus aureus (mrsa) is a common major human pathogen that causes hospital-acquired infections. characterization and typing of the staphylococcal cassette chromosome has led to a better understanding of mrsa infection cycle in hospital. the meca-associated hypervariable region size classifies mrsa isolates that colonized in nasal carriers. objectives: t...

OBJECTIVE We attempted to determine if an increase in resistance to ciprofloxacin occurred among nosocomial pathogens, especially Pseudomonas aeruginosa and Staphylococcus aureus. METHODS We examined 1989-1992 ciprofloxacin susceptibility results from 8,517 P aeruginosa and 9,021 S aureus isolates associated with nosocomial infections reported to the National Nosocomial Infections Surveillanc...

Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly a cause of nosocomial and community-onset infection with unknown national scope and magnitude. We used the National Hospital Discharge Survey to calculate the number of US hospital discharges listing S. aureus-specific diagnoses, defined as those having at least 1 International Classification of Diseases (ICD)-9 code specific fo...

BACKGROUND AND PURPOSE Nosocomial infection contributes to the morbidity and mortality of patients in hospital. Timely microbiologic surveillance and assessment of antimicrobial resistance is important for dealing with nosocomial infections. This retrospective review was conducted to evaluate the microbiologic spectrum and susceptibility pattern in the pediatric intensive care unit from 2001 to...

In the last two decades, epidemiological data from United States national administrative databases and population-based studies have shown a two to six-fold increase in the incidence of Clostridium difficile infection (CDI), especially in the elderly [1-3]. This increase has been observed in diverse settings with C. difficile replacing methicillin resistant Staphylococcus aureus (MRSA) as the m...

Mutations in the staphylococcal virulence regulator gene agr frequently occur during Staphylococcus aureus infection. Whether agr-defective strains are fit for colonization, an important prerequisite for infection, is unknown. Screening by means of assays to detect delta-hemolysin activity and agr autoinducing peptide production indicated that 15 ( approximately 9%) of 160 healthy human subject...

Methicillin-resistant Staphylococcus aureus is a common and continuously growing cause of nosocomial and community-acquired infections. The type, disease severity, and clinical outcomes of these infections, as well as the genotypic and susceptibility patterns of the bacteria differ according to the setting in which the infection occurs-a healthcare facility or the community setting. The inciden...