BACKGROUND Nonalcoholic fatty liver disease has become a worldwide challenge. Liver biopsy remains the single most reliable approach to determine the severity of this disease. As patients with nonalcoholic fatty liver disease require close follow-up, performing this invasive method repeatedly seems impractical; therefore, designing a noninvasive system to follow up patients has become a common ...

In several genome-wide association studies, nonalcoholic fatty liver disease and alanine aminotransferase susceptibility variants have been identified in several genes, including LYPLAL1, ZP4, GCKR, HSD17B13, PALLD, PPP1R3B, FDFT1, TRIB1, COL13A1, CPN1, ERLIN1, CWF19L1, EFCAB4B, PZP, and NCAN. To investigate the relationship between these genes and nonalcoholic fatty liver disease in the Japane...

nonalcoholic fatty liver disease (nafld) is increasing in pediatric age group parallel to the growing prevalence of obesity and overweight all around the world. so changing in life style and   interventions on obesogenic environment is cornerstone of nafld therapy in obese children. some experts recommend that children and adolescents be encouraged to follow a low-fat, low-glycemic-index diet t...

Objective:To assess the role of plasma pentraxin-3 in Nonalcoholic fatty liver disease (NAFLD)among Egyptian patients.

Objective: To study the levels of serum adiponectin and chemerin in patients with nonalcoholic fatty liver disease(NAFLD) their diagnostic role.

IMPORTANCE Nonalcoholic fatty liver disease and its subtype nonalcoholic steatohepatitis affect approximately 30% and 5%, respectively, of the US population. In patients with nonalcoholic steatohepatitis, half of deaths are due to cardiovascular disease and malignancy, yet awareness of this remains low. Cirrhosis, the third leading cause of death in patients with nonalcoholic fatty liver diseas...

background: green tea is one of the most popular beverages in the world. it is believed to have beneficial effects in the prevention and treatment of many diseases, one of which is nonalcoholic fatty liver disease (nafld). the present study investigated the effects of consumption of green tea in nafld patients. methods: this study was a double‑blind, placebo‑controlled, randomized clinical tria...

The underlying causes of nonalcoholic fatty liver disease are unclear, although recent evidence has implicated the endoplasmic reticulum in both the development of steatosis and progression to nonalcoholic steatohepatitis. Disruption of endoplasmic reticulum homeostasis, often termed ER stress, has been observed in liver and adipose tissue of humans with nonalcoholic fatty liver disease and/or ...

CONTEXT Limited clinical data suggest Helicobacter pylori (Hp) infection may contribute to nonalcoholic fatty liver disease (NAFLD) pathogenesis. OBJECTIVES The effect of Hp eradication on hepatic steatosis (magnetic resonance imaging), nonalcoholic fatty liver disease fibrosis score and HSENSI (Homocysteine, serum glutamic oxaloacetic transaminase, Erythrocyte sedimentation rate, nonalcoholi...