نتایج جستجو برای: non small cell lung
تعداد نتایج: 3512205 فیلتر نتایج به سال:
Background: Apelin has recently been considered as an adipokine secreted from visceral fat. Apelin and itsreceptor exist in many tissues including lung and play significant roles in many physiological andpathological activities. However, serum level of apelin-12 is unknown in smokers and in various types of lungmalignancies. There...
Background: It is well known that, at the time of the initial presentation of patients with non-small cell lung cancer, N-status is very important in accurate staging and avoiding inappropriate surgical procedures. Also, if mediastinal lymph node metastasis (N2) of non-small cell lung cancer (stage IIIA) is present, neoadjuvant (preoperative) chemora-diotherapy is indicated therefore a quick an...
the lung cancer is one of the most dangerous cancers and is also the leading cause of cancer death worldwide, accounting for about 1.3 million deaths annually. however in clinical practice, lung cancer therapies commonly do with chemotherapy, although it is hard because the lung cancer may progress to metastasis stage. the metastasis of lung cancer is highly dependent of expression of matrix me...
Objective(s): Lymph node metastases are the most significant prognostic factor in localized non-small cell lung cancer (NSCLC). Identification of the first nodal drainage site (sentinel node) may improve detection of metastatic nodes. Extended surgeries, such as lobectomy or pneumonectomy with lymph node dissection, are among the therapeutic options of higher acceptab...
Background: Lung cancer is the most common cause of cancer death worldwide with an annual mortality rate of more than 1.3 million worldwide. We aimed to analyze the clinicopathological features of patients with non-small-cell lung cancer (NSCLC) in west of Iran. Methods: 64 patients with NSCLC who referred to our clinic were analyzed. Sex, age, histopathology, location of the tumor, treatment,...
Background: Tumor radioresistance leads to a reduction in the efficiency of radiation therapy. It is very important to explore the cellular mechanisms leading to radioresistance and to find potential therapeutic targets, which might improve the efficacy of radiation therapy. This study was to investigate the role of ataxia-telangiectasia mutated (ATM) and murine double minute X (MDMX) in radior...
H Endon et al (JCO 2004;22:811-9). Selected 8 genes out of 44 detected as prognostic markers of adenocarcinoma (Garber et al PNAS USA 98;13784-9, 2001 and Bhattachorjee et al PNAS USA 98;13790-5, 2001): PTK 7 (HR 0.5), CIT (HR 0.6), SCNNIA (HR 1.7), PGES (HR 2.2), EST-LB4D (HR 1.9), ERO 1l (HR 0.2), EST-AA434256 (HR 0.4) and ZWINT (HR 2.3). Low risk group had a 85% 5 y OS and high risk 40% 5 y OS.
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