background: in this study the level of il-23 and il-27 produced by macrophages derived from peri­pheral blood mononuclear cell culture collected from patients with healing or non-healing form of cutane­ous leishmaniasis lesion were compared before and after treatment with live leishmania to explore whether il-23 or il-27 plays any role in healing process of cutaneous lesions induced by l. major...

Squamous cell carcinoma (SCC) of the skin is one of the mostcommon non melanoma skin cancers (NMSC), along withbasal cell carcinoma (BCC). Besides ultraviolet radiation,exposure to industrial agents, ionizing radiation, and areas ofchronic inflammation are associated with the development ofSCC. Squamous cell carcinoma may also be associated withforeign bodies. We report a rare case of cutaneous...

In a long-term cohort study, we calculated cancer incidences and survival rates after the development of these cancers in kidney-transplant recipients. The cancer incidences were compared with those in the general population. The occurrence of cancer was recorded in all patients who received kidney transplantation between 1966 and 2006. The median follow-up time was more than 9 years with a max...

Prior to the introduction of the ileal conduit more than four decades ago, the options for urinary diversion after cystectomy were extremely limited. Direct cutaneous anastomoses of the collecting system (cutaneous pyelostomies, ureterostomies) offered patients a short-term diversion, but the benefits were outweighed by significant complications: recession or stenosis of the stoma. The first ch...

Cutaneous squamous cell carcinoma is one of the most common non-melanoma skin cancers worldwide. While most cutaneous squamous cell carcinomas are easily managed, there is a high-risk subset of tumors that can cause severe morbidity and mortality. Tumor characteristics as well as patient characteristics contribute to the classification of cutaneous squamous cell carcinomas as low-risk vs. high-...

Background & Objective: Abdominal cutaneous and subcutaneous nodules are uncommon lesions which may be benign or malignant. Majority of the malignant nodules are metastatic in origin and may be the initial presentation of primary malignancy, hence an early diagnosis is important. Our aim was to find out the spectrum of lesions (both non-neoplastic and neoplastic) that present as cutaneous and s...

To test the hypothesis that cutaneous active vasodilation in heat stress is mediated by a redundant cholinergic cotransmitter system, we examined the effects of atropine on skin blood flow (SkBF) increases during heat stress in persons with (CF) and without cystic fibrosis (non-CF). Vasoactive intestinal peptide (VIP) has been implicated as a mediator of cutaneous vasodilation in heat stress. V...

Background: Abdominal cutaneous and subcutaneous nodules are uncommon benign or malignant lesions. The majority of the malignant nodules are metastatic in origin and may be the initial presentation of a primary malignancy; hence, an early diagnosis is important. Our aim of this study was to find out the spectrum of lesions (both non-neoplastic and neoplastic) that present as cutaneous and subcu...