Nodular thickening of the atrio-ventricular valves may be conspicuous in the hearts of the elderly. Usually described as senile sclerosis, it is assumed to be an involutional or degenerative process associated with advanced age. The difficulty of distinguishing such changes from the results of other pathological conditions which may have been present earlier in life is well recognized (Gould, 1...

as to histolÃ3gica! type according to the Rye classification, patients with the lymphocytic predominance type of the disease had the best prognosis, those with the nodular sclerosis type had the 2nd best, those with the mixed cellularity type had the 3rd best, and those with the lymphocytic depletion type had the poorest prognosis. In two of the remaining three series, the 5-year survival rate ...

PURPOSE Despite the availability of detailed electroclinical and imaging data, only a few neuropathological studies of nodular heterotopia have been published. The aim of this study was to describe the neuropathological features of various types of nodular heterotopia obtained from patients undergoing surgery for intractable epilepsy. METHODS Specimens of heterotopic nodules taken from 24 pat...

Nodular lesions can be difficult to diagnose under dermoscopy alone, since they often lack specific diagnostic features. Confocal microscopy can be used as an aid to dermoscopy, to increase the diagnostic accuracy on equivocal skin lesions. We report three cases of bluish nodular lesions, difficult to diagnose under dermoscopy alone. Confocal features were very useful in these cases to lead us ...

Although involvement of the heart by malignant lymphoma is relatively common, it is unusual to be detected premortem. We report a case of Hodgkin's lymphoma who presented with systemic signs and symptoms including abdominal distension, weakness, pallor, chills and fever, hepatosplenomegaly and generalize...

A young woman developed Hodgkin's disease (nodular sclerosis) in pregnancy and gave birth to a boy who developed common variable immunodeficiency. Initially there was normal IgG with low IgA and IgM, and antibody deficiency. IgG levels fell progressively over 4 years. Cellular immunity was normal. We suggest that this is a further family with immune deficiency presenting with common variable im...

Focal nodular hyperplasia (FNH) is characterized by the presence a central scar with radiating fibrous septa. Our case had a capsular retraction, which was the result of an extension of the central scar to the surface. In addition, a hypointense scar on the T2-weighted image and a minimal enhancing central scar on the enhanced T1-weighted image, which was due to dense, sclerotic collagenous tis...

Nodular fasciitis is a benign fibroblastic tumour that does not commonly occur in the hand and generally does not exceed 5 cm in size. Given the characteristics of this entity, it demands a differential diagnosis with malignant tumours and infectious processes. We present an unusual case of nodular fasciitis in the palm of the hand, producing a lesion larger than any similar lesion reported pre...