Background: T-type calcium channels and cannabinoid receptors are known to play important roles in chronic pain, making them attractive therapeutic targets. We recently reported on the design, synthesis and analgesic properties of a novel T-type channel inhibitor (NMP-7), which also shows mixed agonist activity on CB1 and CB2 receptors in vitro. Here, we analyzed the analgesic effect of systemi...

OBJECTIVES/HYPOTHESIS To evaluate vocal function after refined nerve-muscle pedicle (NMP) flap implantation with arytenoid adduction (AA) compared with type I thyroplasty with AA for patients with unilateral vocal fold paralysis (UVFP) and to evaluate the degree of patient satisfaction following the refined NMP with AA. STUDY DESIGN A retrospective review of clinical records of 52 patients wi...

OBJECTIVE To evaluate the clinical and cost-effectiveness of non-medical prescribing (NMP). DESIGN Systematic review. Two reviewers independently completed searches, eligibility assessment and assessment of risk of bias. DATA SOURCES Pre-defined search terms/combinations were utilised to search electronic databases. In addition, hand searches of reference lists, key journals and grey litera...

The nuclear receptor NR2E3 promotes expression of rod photoreceptor genes while repressing cone genes. Mice lacking NR2E3 (Nr2e3(rd7/rd7) referred to here as rd7) are a model for enhanced S-cone syndrome, a disease associated with increased sensitivity to blue light and night blindness. Rd7 retinas have reduced levels of the outer segment (OS) structural protein retinal degeneration slow (RDS)....

The primary aims were to study the metabolism in rats and to determine the biological levels after one oral developmentally toxic dose of N-methyl-2-pyrrolidone (NMP), a widely used industrial chemical. Non-pregnant female Sprague-Dawley rats were given an oral single dose of either a non-toxic dose of 125 mg NMP/kg (group 1) by gavage or a developmentally toxic dose of 500 mg/kg (group 2). Blo...

PURPOSE The present study examined the factors affecting the content of impurities of nimodipine (NMP) emulsion and the associated methods of compound protection. METHODS Destructive testing of NMP emulsion and its active pharmaceutical ingredient (API) were conducted, and ultracentrifugation was used to study the content of impurities in two phases. The impurity of NMP was measured under dif...

1. Qyerview of the System. Current approaches to expert systems' reasoning under uncertainty fail to capture the iterative revision process characteris­ tic of intelligent human reasoning. This paper reports on a system, called the Non-monotonic Probabilist, or NMP (Cohen, et al., 1985). When its in­ ferences result in substantial conflict, NMP examines and revises the assump­ tions underlying ...

Background: Nomophobia is the fear of being disconnected from one’s mobile phone, prevailing in modern area. To the best of our knowledge, no Persian psychometric scales are available for investigating nomophobia among Iranians. Therefore, we here aimed to translate and validate the Nomophobia Questionnaire (NMP-Q) for being used in Iran. Methods:...

N-Methyl-2-Pyrrolidone (NMP), which has the chemical formula C5H9NO, is a stable, water-soluble organic solvent that is widely used in the pharmaceutical, petrochemical, polymer science and especially semiconductor industries. Electronic grade NMP is used by semiconductor manufacturers as a wafer cleaner and photoresist stripper and as such the solvent comes into direct contact with wafer surfa...

jlknmpo m knqprnm snmpmpt u tnvpo mpqpw u tnx y9qpo znmp{}|nmpy9qptn|nw { ~8|nmprnmp ~n€ y9~no mWmp  mpvp{ u rnmWw vpknmpy9mpw} ~no-qp€n€n ‚nu tnx ƒ…„g†l‡ rnu |nmp~ vp~n|nu tnx w { qptn|nqpo |ˆ{ ~ˆy9mpmp{0{ knm‰vpknqp  mptnxnmpw  o ~nyŠ{ knm‰mpy9mpo xnu tnx qp€n€n u vpqp{ u ~ntnw ‹Œ m9€no mpw mptn{JqYo mpqp { u y9mYƒ…„g†l‡Žrnu |nmp~vp~n|nu tnx w ‚nw { mpy‰‘u { k u tn ~no y9qp{ u ~...