AIM To show certain health effects associated with acute and chronic exposure to nitrous oxide of staff of the Department of Anaesthesiology and Intensive Care at the Clinical Hospital in Shtip. METHODS A transversal study was conducted, that include 43 health workers (23 - exposed and 20 - unexposed). Personal exposure to nitrous oxide for this group members was assessed through continuous m...

Resting cells of Corynebacterium nephridii reduce nitrate, nitrite, and nitric oxide to nitrous oxide under anaerobic conditions. Nitrous oxide production from nitrite was optimal from pH 7.0 to 7.4. The stoichiometry of nitrous oxide production from nitrite was 99% of the theoretical-two moles of nitrite was used for each mole of nitrous oxide detected. Hydroxylamine increases gas evolution fr...

Nitrous Oxide, our old companion is in use since long. Its two properties analgesia and reduction in MAC of inhalational agent make it a powerful tool in anaesthetic practice. Importance of nitrous oxide can be judged from the fact that sizable percentage of anaesthetists will cancel the elective list if nitrous oxide is not available! Widespread and prolonged use of nitrous oxide has brought i...

Studies of the leucopenic effects of nitrous oxide were made in rodents, with and without surgical wounds. The animals were exposed to one of the following atmospheres: (1) air; (2) 25 per cent nitrous oxide; (3) 60 per cent (rats) or 40 per cent (mice) nitrous oxide; the oxygen percentage was maintained at 21 per cent in each case. A leucopenic effect and suppression of the normal leucocytosis...

A Method for Evaluating Exposure to Nitrous Oxides by Application of Lognormal Distribution: S.S. BORJANOVIC, et al. Department of Work Physiology, Institute of Occupational Health “Dr Dragomir Karajovic”—A lognormal distribution adequately describes exposure to nitrous oxides in a work environment. The aim of this paper was to assign to the measured data a certain degree of variability which d...

BACKGROUND Globally there are >200 million major surgical procedures undertaken annually, and about 20% of these involve patients who have coronary artery disease. Many receive nitrous oxide, which impairs methionine synthase, thus inhibiting folate synthesis and increasing postoperative homocysteine levels. Nitrous oxide anesthesia leads to postoperative endothelial dysfunction, and there is s...

background anxiety is an unpleasant experience that may have adverse effects on the process of anesthesia, cesarean delivery, recovery period and postoperative pain. anxiety can also affect maternal satisfaction of the medical cares that provided by the medical team. objectives to compare the effects of inhalational 50% nitrous oxide (n2o) with oxygen on reducing anxiety and pain in parturients...

a 50 year-old man was referred with history of acute ataxia and lower extremity paresthesia 10 days after general anesthesia with nitrous oxide. cervical mri showed long hypersignal lesion in posterior segment of the cord. blood analysis revealed vitamin b12 deficiency. nitrous oxide-induced myelopathy should be considered in patients who develop acute neurological manifestation after general a...

We postulated that nitrous oxide transfer into the pleural cavity can occur by diffusion from the alveoli, independent of vascular transport. Under general anaesthesia, six sheep were studied in two phases, a control and an experimental phase. The sheep were anaesthetized, intubated, and received positive pressure mechanical ventilation. A catheter was placed in the right pleural cavity and 150...