نتایج جستجو برای: nitrile oxides

تعداد نتایج: 23315  

Journal: :Bioorganic & medicinal chemistry 2006
Giovanni Romeo Daniela Iannazzo Anna Piperno Roberto Romeo Monica Saglimbeni Maria Assunta Chiacchio Emanuela Balestrieri Beatrice Macchi Antonio Mastino

Phosphonated isoxazolinyl nucleosides have been prepared via 1,3-dipolar cycloaddition reaction of nitrile oxides with corresponding vinyl or allyl nucleobases for antiviral studies. The cytotoxicity, the anti-HSV activity and the RT-inhibitory activity of the obtained compounds were evaluated and compared with those of AZT and diethyl{(1'SR,4'RS)-1'-[[(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1...

In this study, reactions of the simple cycloalkynes with substituted Nitrile Oxides, by DFT method will be discussed. The investigation of the structural properties, theoretical thermodynamic and kinetic data, i.e., the activation free energies(DG*), the free energies changes of reaction(DrG) and rate constants of the reactions (k) in 298 K and effects of Electron-withdrawing and...

Journal: :Bulletin of the Chemical Society of Japan 1981

Journal: :Bulletin of the Chemical Society of Japan 1978

2010
Volker Jäger Wolfgang Frey Yaser Bathich Sunitha Shiva Mohammad Ibrahim Marco Henneböhle Pierre-Yves LeRoy Mukhtar Imerhasan

2-Isoxazolines represent a well known class of heterocycles, readily accessible in particular by 1,3-dipolar cycloaddition of nitrile oxides to alkenes. 2-Isoxazolines are easily transformed into 2isoxazolinium salts by N-methylation, and further into 3-isoxazolines by deprotonation. In contrast to the parent system, less is known concerning the chemistry of the derived classes, and potential a...

Journal: :Polymer 2021

Nitrile N-oxides are useful reagents and crosslinkers for catalyst- byproduct-free 1,3-dipolar cycloaddition reactions. The stability of nitrile can be enhanced by introducing bulky substituents, whereas their reactivity decreases concomitantly. Herein, an isolatable aliphatic ditopic N-oxide was synthesized applied to catalyst-free crosslinking unsaturated bond-containing polymers. By decreasi...

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