نتایج جستجو برای: nitric oxide system
تعداد نتایج: 2390409 فیلتر نتایج به سال:
The metabolism of nitric oxide in Paracoccus denitrificans has been studied using a Clark-type electrode. The uncoupler carbonyl cyanide m-chlorophenylhydrazone (CCCP) and the SH reagent N-ethylmaleimide, both of which released nitric oxide from cells respiring nitrite, were found to be efficient inhibitors of nitric oxide reductase activity. Control experiments with another uncoupler, pentachl...
اثر تجویز توأم مورفین و ال- آرﮊینین در ناحیه CA3 هیپوکامپ بر یادگیری و حافظه فضایی موشهای صحرایی نر
Background: Learning and memory are the complicated agents of central nervous system that various regions of brain can be involved in these phenomena, especially regions like hippocamp. Various agents like nitric oxide and morphine can influence learning and memory. About the effects of morphine with other components there was not clear reports so in this study the effect of co-administrati...
nitric oxide (no) is a molecule required for many physiological functions, produced from l-arginine by no synthases (nos). it is a free radical, producing many reactive intermediates that account for its bioactivity. sustained induction of the inducible form of nos (inos) in chronic inflammation may be mutagenic, through no-mediated dna damage or hindrance to dna repair, and thus potentially ca...
objective(s): endometriosis is a complex gynecologic disease with unknown etiology. noscapine has been introduced as a cancer cell suppressor. endometriosis was considered as a cancer like disorder, the aim of present study was to investigate noscapine apoptotic effect on human endometriotic epithelial and stromal cells in vitro. materials and methods:in this in vitro study, endometrial biopsie...
Nitric oxide provokes vasodilation and inhibits platelet aggregation. We examined the effect of nitric oxide on superoxide anion production by three sources: activated intact neutrophils, xanthine oxidase/hypoxanthine, and the NADPH oxidase. Nitric oxide significantly inhibited the generation of superoxide anion by neutrophils exposed to either FMLP (10(-7)M) or PMA (150 ng/ml) (IC50 = 30 micro...
The innate host response to virus infection is largely dominated by the production of type I interferon and interferon stimulated genes. In particular, fibroblasts respond robustly to viral infection and to recognition of viral signatures such as dsRNA with the rapid production of type I interferon; subsequently, fibroblasts are a key cell type in antiviral protection. We recently found, howeve...
Objective: In this research, the effect of intranasal and subcutaneous BCG vaccination was compared on nitric oxide production by peritoneal macrophages and the load of parasite burden in liver and spleen of infected BALB/c mice. Materials & Methods: Twenty male 6-8 weeks old BALB/c mice were vaccinated with appropriate dose of BCG through intranasal and subcutaneous routs. They received au...
Background Acute and chronic effects of nitric oxide on oxidative stress and neuronal demyelination have been reported in human and animal models. Objective Oxidative stress is involved in the pathogenesis of demyelinated animals; thus, this study investigated the effects of nitric oxide system and ethidium bromide on oxidative stress in the hippocampal formation. Methods This experimental...
We have evaluated the effect of delivering nitric oxide using a continuous flow system (CFS) or two commercially available proportional gas injection systems (PGIS), Nodomo (Dräger, Lübeck, Germany) and Pulmonox-Mini (Messer Griesheim Austria, Gumpoldskirchen, Austria) on measured and simulated concentrations of nitric oxide. Nitric oxide concentration was measured in a bench test at five sites...
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