OBJECTIVE To compare 3 methods of clinical assessment of jaundice in newborns by home health nurses. DESIGN Prospective clinical trial. SETTING Homes of newborns living within 10 miles of a 340-bed community hospital where they were delivered. PARTICIPANTS Home health nurses and newborn patients (< or =2 weeks old). INTERVENTIONS The nurses examined the newborns and documented whether t...

BACKGROUND Morbidity and mortality rates of low birth weight (LBW) newborns at term are higher than rates in normal birth weight (NBW) newborns. LBW newborns are at greater risk to acquire recurrent bacterial and viral infections during their first few weeks of life possibly as an outcome of compromised innate immune functions. As adaptive immunity is in a naive state, increased risk of infecti...

BACKGROUND Neonatal encephalopathy following birth asphyxia is a major predictor of long-term neurological impairment. Therapeutic hypothermia is currently the standard of care to prevent brain injury in asphyxiated newborns but is not protective in all cases. More robust and versatile treatment options are needed. Angiogenesis is a demonstrated therapeutic target in adult stroke. However, no s...

OBJECTIVES To determine the value of clinical foetal distress in predicting early perinatal outcome. DESIGN Prospective cohort study. SETTING Kenyatta National Hospital. SUBJECTS Fifty eight newborns delivered via Caesarian section with a diagnosis of clinical foetal distress were compared with another group of 58 newborns delivered similarly, but without clinical foetal distress. RESUL...

BACKGROUND Ventilator treatment exposes newborns to both hyperoxemia and hyperventilation. It is not known how common hyperoxemia and hyperventilation are in neonatal intensive care units in Norway. The purpose of this study was to assess the quality of current care by studying deviations from the target range of charted oxygenation and ventilation parameters in newborns receiving mechanical ve...

BACKGROUND Early readmissions of apparently healthy newborns after discharge from well baby nurseries (WBN) may reflect an inadequate assessment of the newborn's readiness for discharge. OBJECTIVE To determine the frequency, causes, costs, and variations in rates of early rehospitalization of newborns discharged from 21 WBNs in 1 health care system. METHODS We queried the Enterprise Data Wa...

Introduction. Recent studies in Mexico have shown that from 20/10,000 to 58/10,000 newborns with Toxoplasma infection could be undetected. The aim of this study was to determine the weighed prevalence of T. gondii infection and describe the epidemiological transition of infection in newborns. Methods. Research literature reporting Toxoplasma infection prevalence in Mexican newborns and children...

purpose: to determine the normal conjunctival flora in neonates and infants. methods: conjunctival specimens were obtained from both eyes of 43 newborns delivered by cesarean section (c/s) and 53 newborns delivered by normal vaginal delivery (nvd) as well as 54 healthy infants in two maternity and pediatric hospitals. the specimens were cultured aerobically, anaerobically and for fungi. results...

BACKGROUND The use of cancer-related biomarkers in newborns has been very limited. OBJECTIVE We investigated the formation of micronuclei (MN) in full-term and preterm newborns and their mothers from the Rhea cohort (Crete), applying for the first time in cord blood a validated semiautomated analysis system, in both mono- and binucleated T lymphocytes. METHODS We assessed MN frequencies in ...

Carnitine plays an important role in energetic metabolism. The aim of the study was to characterize the carnitine status in term and preterm newborns with respect to gestational age, birth weight, haematocrit and red blood cell count (RBC). The effect of nutrition on carnitine levels in the first week of life was also studied. Total blood pool of free carnitine (FC), acylcarnitines (AC) and tot...