Houshiheisan is composed of wind-dispelling (chrysanthemun flower, divaricate saposhnikovia root, Manchurian wild ginger, cassia twig, Szechwan lovage rhizome, and platycodon root) and deficiency-nourishing (ginseng, Chinese angelica, large-head atractylodes rhizome, Indian bread, and zingiber) drugs. In this study, we assumed these drugs have protective effects against cerebral ischemia, on ne...

PURPOSE Penetration of the clivus is required for surgical access of the brain stem. The endoscopic transclivus approach is a difficult procedure with high risk of injury to important neurovascular structures. We undertook a novel anatomical and radiological investigation to understand the structure of the clivus and neurovascular structures relevant to the extended trans-nasal trans-sphenoid p...

This analytical review presents data on brain injury in surgical management of congenital heart disease. A brief description mechanisms and methods its prevention are given, moreover, a clinical case applying such techniques is given. The neurovascular unit vitro model advantages presented. protocol for modelling, the further application model, prospects using it studying intraoperative hypoxia...

Cortical spreading depolarization causes a breakdown of electrochemical gradients following acute brain injury, and also elicits dynamic changes in regional cerebral blood flow that range from physiological neurovascular coupling (hyperaemia) to pathological inverse coupling (hypoperfusion). In this study, we determined whether pathological inverse neurovascular coupling occurred as a mechanism...

BACKGROUND AND PURPOSE Cerebral ischemia initiates cascades of pathological events such as edema, blood-brain barrier breakdown, and tissue degeneration. Thrombin activation is a key step in coagulation, and thrombin has recently been shown to mediate endothelial permeability and cellular toxicity in vitro. We examined the effect of thrombin on vasculature during ischemia in vivo. METHODS Foc...

conclusions bilateral anterior shoulder dislocation is very rare. the excessive traction force during closed reduction may lead to nerve palsy. clear documentation of neurovascular status and adequate imaging before and after a reduction should be performed. introduction unilateral anterior shoulder dislocation is one of the most common problems encountered in orthopedic practice. however, simu...

This article describes a traumatic complete anterior knee dislocation of a previously well-functioning total knee arthroplasty. A thorough physical examination with appropriate radiographic imaging study is required for proper evaluation and treatment of this injury, as it is often associated with neurovascular injury and subsequent global instability of the injured knee is likely.

Neurovascular injury may occur during ankle arthroscopy. The majority of complications are neurological injuries; however, vascular injuries do exist. Neurovascular structures are especially vulnerable during portal placement and debridement of anterior structures. Routine anteromedial and anterolateral portals are generally accepted to be safe; this is different from the anterocentral portal, ...

T he glenohumeral joint is the most mobile and one of the most frequently dislocated joints in the human body. Before skeletal maturity, shoulder dislocations are less frequent, and shoulder trauma more often results in fracture through the proximal humeral physis. In a recent epidemiologic study, Zacchilli and Owens found that shoulder dislocations follow a bimodal distribution, with 46.8% occ...

Background: The purpose of this study was to introduce a technical tip for the preparation of tibial tunnel in a posteriorcruciate ligament (PCL) reconstruction to reduce the chance of popliteal artery injury and duration of the surgery.Methods: This study included 18 patients who underwent PCL reconstructions at Imam Khomeini University Hospital,Tehran, Iran, between 2016 and...