OBJECTIVE We screened the human aldose reductase (ALR) gene for DNA sequence variants in type 2 diabetic and nondiabetic subjects and investigated whether the previously reported and novel polymorphisms were associated with neurophysiologic deterioration and clinical peripheral neuropathy. RESEARCH DESIGN AND METHODS The study population included 85 Finnish type 2 diabetic and 126 nondiabetic...

Peroneal neuropathy is one of the common focal mononeuropathies in the lower extremities occurring in both adults and children. Foot drop due to weakness of ankle dorsiflexion is the most common presentation of a peroneal neuropathy. It may also result from other causes involving the upper or lower motor neurons. Disorders that must be distinguished from peroneal neuropathy include sciatic mono...

Mismatch negativity (MMN) reportedly reflects the neurophysiologic detection of acoustic differences, rather than the phonemic categorization of speech sounds. The purpose of the present study was to determine if it is elicited by speech contrasts that are acoustically different but are not differentiated by listeners in behavioral tasks. Experimental stimuli were drawn from a synthetically gen...

Recent advances in our knowledge of the neurophysiologic mechanisms underlying sleep and experimental states of coma (1) suggest the need for a neurophysiologic approach to the many complex clinical syndromes associated with disturbance of consciousness. The coma syndrome associated with hepatic disease and usually known as hepatic coma was chosen for investigation since it presents a good exam...

SUMMARY This review article introduces the reader to the very basics of electroencephalography (EEG). It tries to explain in simple terms the physiologic principles of EEG generation and organization at the cellular, cortical and subcortical levels. It also introduces the basic EEG terminology (see the key words).

A catalog record for this publication is available from the British Library Library of Congress Cataloging in Publication data Intraoperative neurophysiologic monitoring / Gloria M. Galloway. .. [et al.]. p. ; cm. Includes bibliographical references and index. Cambridge University Press has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites r...