to compare intubating conditions and hemodynamic changes between bonfils intubation fiberscope and macintosh laryngoscopy without administering neuromuscular blocking drugs (nmbds). methods: in this randomized controlled trial,80 male and female patients, scheduled for elective surgery, aged 15 to 60 years, asa class ii or i, non-obese, non smokers, without anticipated difficult intubation; wer...

We read with interest the study by Lu et al. about routine sugammadex reversal in patients with rocuroniuminduced neuromuscular blockade undergoing thyroidectomy. This study showed that after a single intubating dose of rocuronium, sugammadex 2 mg/kg was effective to restore sufficient neuromuscular function, allowing intraoperative neuromonitoring (IONM). Also, this article concluded that impl...

Neuromuscular blocking agents are used to facilitate tracheal intubation in patients undergoing ambulatory surgery. The use of high-dose neuromuscular blocking agents to achieve muscle paralysis throughout the case carries an increased risk of residual post-operative neuromuscular blockade, which is associated with increased respiratory morbidity. Visually monitoring the train-of-four (TOF) fad...

BACKGROUND In most publications about myasthenia, monitoring neuromuscular blockade during anesthesia is recommended. In healthy patients, the relation of blockade between muscles has been established, but there is little information about the relation in myasthenic patients. Our objective was to investigate whether the relation between the orbicularis oculi and adductor pollicis muscles is the...

PURPOSE OF REVIEW To revise the current literature on concepts for neuromuscular block management. Moreover, consequences of incomplete neuromuscular recovery on patients' postoperative pulmonary outcome are evaluated as well. RECENT FINDINGS The incidence of residual paralysis may be as high as 70% and even small degrees of residual paralysis may have clinical consequences. Neostigmine shoul...

The effects on neuromuscular blockade by d-tubocurarine and succinylcholine of inhibition of prostaglandin biosynthesis by indomethacin and of intra-arterial administration of prostoglandins E2 and F2 alpha, before and after inhibition of prostoglandin biosynthesis, were evaluated in the cat sciatic-tibialis preparation. Non-specific inhibition of prostaglandin biosynthesis by indomethacin 3 mg...

The number of elderly patients is increasing worldwide. This will have a significant impact on the practice of anesthesia in future decades. Anesthesiologists must provide care for an increasing number of elderly patients, who have an elevated risk of perioperative morbidity and mortality. Complications related to postoperative residual neuromuscular blockade, such as muscle weakness, airway ob...