Neurologic manifestations of lymphomatoid granulomatosis occur in 20-30% of cases. The disease is primarily an unusual form of pulmonary angiitis, and was first described in 1972 by Liebow et al. [1] . The purpose of this paper is to show the progression and regression of CNS lesions in a 17-year-old boy who presented only with neurologic features of the disease. Patients with lymphomatoid gran...

Posterior reversible encephalopathy syndrome (PRES) is a clinical associated with certain underlying conditions or medications, spectrum of neurologic findings and characteristic neuroimaging. We describe case PRES in 3-year-old girl positive for SARS-CoV-2 no other risk factors the development this syndrome. review suggest plausible mechanisms involvement patients SARS-CoV-2.

: Coronavirus disease 2019 (COVID-19) was officially declared as a pandemic on March 11, 2020. Although most patients with COVID-19 manifest fever and respiratory tract symptoms, extrapulmonary atypical presentations, such gastrointestinal, neurologic, cardiovascular involvement well thromboembolic events have been reported amongst patients. Herein, we aim to describe patient who progressed pur...

BACKGROUND Crohn's disease (CD) and ulcerative colitis (UC), widely known as inflammatory bowel diseases (IBD), are thought to result from an inappropriate activation of the mucosal immune system driven by intestinal bacterial flora. METHODS Although the extraintestinal manifestations of IBD are well documented, the association of IBD with neurologic and neuromuscular involvement is rare and ...

Systemic Lupus Erythematosus (SLE) is a complex clinical syndrome which its components are less clearly recognized and includes heterogeneous demonstrations engaging both central and peripheral nervous system along with disabling effects. This disease is called "thousand faces" due to these heterogeneous demonstrations. This gap exists while 75% of adults and children with SLE may dea...

BACKGROUND Neurologic impairment is not considered a clinical manifestation of diskitis in children and has seldom been associated with it in the medical literature. OBJECTIVE To describe neurologic findings and their implications in children with diskitis. STUDY DESIGN Retrospective medical records review of children discharged with a diagnosis of diskitis between January 1992 and December...

Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative treatment for Griscelli syndrome type 2, an inherited immune disorder causing fatal hemophagocytic lymphohistiocytosis (HLH). Optimal therapeutic modalities are not yet well known. We retrospectively analyzed the outcome for 10 patients who underwent HSCT in a single center between 1996 and 2008. Seven patients (70%)...

MPS represents a group of rare hereditary disorders characterized by multisystem involvement due to intralysosomal GAG accumulation. Among various tissues, both the central and peripheral nervous system are affected in almost all types of the disease. Thus, brain and spinal MR imaging are valuable tools for the assessment of neurologic involvement, and there is evidence that they might be relia...

Behçet disease is a rare multisystem immune-related vasculitis that is prevalent in Japan, the Middle East, and many Mediterranean countries. In our study population of 36 patients with Behçet disease, 16 (44%) had CNS involvement. CT was noncontributory, except in a single patient with dural sinus thrombosis. MR imaging in nine patients showed foci of high signal intensity on T2-weighted image...

Central nervous system symptoms in patients with primary Sjogren`s syndrome are rare. They can present as extraglandular manifestations and require a differential diagnosis from multiple sclerosis. Due to a variety of presentations, Sjogren`s syndrome with neurologic involvement may be difficult to diagnose. Here, we report a case of a 75-year-old woman who was first diagnosed with multiple scl...