nancy, as exemplified by the onset of lupus erythematosus which is related to a rise in progesterone and prolactin. Accordingly, the blocking of estrogen and prolactin was shown to be beneficial in both experimental animals and patients. The reviews by Dr. Esther Sternberg and by Dr. Adriana del Rey support the notion that neuroimmune regulation underlies lymphoproliferative and rheumatic disea...

tional B-cell subsets in the mouse. J Immunol 1980; 125: 2526. 20. Hess AD. Tutschka P·l. Effect of cyclosporin A on human lymphocyte retilJonSeS in vitro. Cs-A allows for the expression of alloantigen-activated suppressor cells while preferentially inhibiting the induction of cytolytic effector lymphocytes in MLR. J Immunol 1980; 124: 260l. 21. Ferguson RM, Fidelus-Gort R. The immunosuppressiv...

Aim: The vagal neuroimmunomodulation (NIM) index is reflective of the cholinergic inflammatory tone in many clinical circumstances as well healthy individuals. We aimed to investigate relationship NIM-index on course patients with PAH.
 Material and Method: A total 31 diagnosed pulmonary arterial hypertension (PAH) were included this study. Data electrocardiography (ECG) C-reactive protein...

Alzheimer disease (AD) is the most common cause of dementia in people over 60 years old. The molecular and cellular alterations that trigger this disease are still diffuse, one of the reasons for the delay in finding an effective treatment. In the search for new targets to search for novel therapeutic avenues, clinical studies in patients who used anti-inflammatory drugs indicating a lower inci...

Severe injury and infection are associated with autonomic dysfunction. The realization that a dysregulation in autonomic function may predispose a host to excessive inflammatory processes has renewed interest in understanding the role of central nervous system (CNS) in modulating systemic inflammatory processes. Assessment of heart rate variability (HRV) has been used to evaluate systemic abnor...

BACKGROUND The cholinergic anti-inflammatory pathway (CAP) modulates inflammatory responses through the vagus nerve and the α-7-nicotinic acetylcholine receptor (α7nAChR) on macrophages and immune cells. Sympathetic/parasympathetic imbalance and chronic inflammation are both linked to poor outcome in dialysis patients. The aim of this study was to investigate CAP activity in these patients. M...

BACKGROUND There is growing interest in the role of microbial agents in the causation of psychiatric disorders. The neurotropic protozoan parasite Toxoplasma gondii is one of the main candidates and has been associated with various psychiatric conditions, including schizophrenia. METHODS A narrative review of the literature from the main medical databases (Medline, PubMed, PsycINFO), Google S...