Abstra ct . An information processing tas k th at generates combinato rial explosion and program complexity when tr eated by a serial algorithm is investi gat ed using both genet ic algorit hms and a neur al network model. The tas k in question is to find a target memory from a set of stored entries in the form of "at t ractors" in a high-dimensional state space. The representation of entries i...

P roblems requiring inferencing with Boolean logic have been implemented in percept rons or feedforward networks, and some attempts have been made to implement fuzzy logic based inferencing in similar networks. In this pap er, we present producti ve networks , which are art ificial neur al networks, meant for fuzzy logic based inferencing. The nod es in t hese networks collect an offset product...

Endocytosis of the transmembrane ligands Delta (Dl) and Serrate (Ser) is required for the proper activation of Notch receptors. The E3 ubiquitin ligases Mindbomb1 (Mib1) and Neuralized (Neur) regulate the ubiquitination of Dl and Ser and thereby promote both ligand endocytosis and Notch receptor activation. In this study, we identify the alpha1,4-N-acetylgalactosaminyltransferase-1 (alpha4GT1) ...

ease. The underlying metabo lic defect i s deficiency of lysosomal enzyme cer amidetrihexosidase. The disease has multisystem i nvo lvement. Neur ol og ical man ifestations i ncl ude smal l-fiber po lyneuropathy man ifested as painful distal extr emities and anhidrosis. Fabry’s disease also presents with both s ma ll -v ess el a nd cor ti cal mu l ti pl e cerebral i nfarcts. Enzyme-replacement ...

L’apprentissage du travail de l’apparence constitue une composante importante la pratique twirling bâton. Partant ce constat, cet article donne à voir le corps idéal promu par l’institution sportive et met en récit les désajustements corporels éprouvés athlètes féminines face l’avancée âge. Prenant pour objet des jeu...

Argon is a noble gas in group 18 of the periodic table. Certificated to exist in air atmosphere merely one century ago, discovery of argon shows interesting stories of researching and exploring. It was assumed to have no chemical activity. However, argon indeed present its biological effect on mammals. Narcotic effect of argon in diving operation and neur-protective function of argon in cerebra...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 207 No. 3 351–363 www.jcb.org/cgi/doi/10.1083/jcb.201407071 JCB 351 Correspondence to François Schweisguth: [email protected] Abbreviations used in this paper: APF, after puparium formation; BAC, bacterial artificial chromosome; Cad, cadherin; FRET, Forster resonance energy transfer; IQR, interquartile range; krz, kurtz; lgd, lethal(2...

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