The expression of some genes increases or decreases the expression of other genes forming a complex network of interactions. Typically, correlations between the expression of different genes under different conditions have been used to identify specific regulatory links between specific genes. Instead of that “bottom up” approach, here we try to identify the global types of networks present fro...

These supporting online materials have 9 sections. Section 1 describes the known population and summation methods of personal network size estimation and how we used the data from our study to decide between them. These personal network size estimates are used in the network scale-up and generalized network scale-up estimates described in Sections 2 and 3. Next, Sections 4 and 5 describe the mu...

A scale-up design procedure, based on a new physical mass transfer (PMT) model, whichdescribes the performance, for aerobic rotating biological contactors (RBC’s) is developed. This scale-up procedure can be used to determine the disc surface area needed to prevent an oxygen limitation or to obtain a specific degree of treatment. In contrast to the empirical, and most previous RBC performance m...