Abstract Given a family $\mathcal{F}$ of bipartite graphs, the Zarankiewicz number $z(m,n,\mathcal{F})$ is maximum edges in an $m$ by $n$ graph $G$ that does not contain any member as subgraph (such called -free ). For $1\leq \beta \lt \alpha 2$ , graphs $(\alpha,\beta )$ - smooth if for some $\rho \gt 0$ and every $m\leq n$ $z(m,n,\mathcal{F})=\rho m n^{\alpha -1}+O(n^\beta . Motivated their w...

Mutational inactivation of the adenomatous polyposis coli (APC) tumor suppressor initiates most hereditary and sporadic colon carcinomas. Although APC protein is located in both the cytoplasm and the nucleus, the protein domains required to maintain a predominantly cytoplasmic localization are unknown. Here, we demonstrate that nuclear export of APC is mediated by two intrinsic, leucine-rich, n...

This paper describes the development of a maturity model to assess the Web-2.0-ness of websites. The model draws on O’Reilly’s Web 2.0 principles and patterns. It distinguishes six dimensions with four degrees of 2.0-ness each. The rating scheme has been evaluated and refined to improve inter-rater reliability in a discussion and a coding iteration. This model raises awareness for 2.0-ness, hel...

Nonequilibrium stationary states (NESS) describe the state of a mechanical system driven and maintained out of equilibrium by external forces. The main characteristic of a NESS is that it sustains sustain steady flows or equivalently that it exhibits positive entropy production. We discuss general features of the fluctuations of the entropy production and corresponding flows. The NESS and the e...

background: posttraumatic and/or postsurgical knee stiff ness is one of the orthopedic complications which is difficult to be treated and can affect individual’s life negatively. the aim of this study is to investigate the results of quadricepsplasty in patients with knee stiff ness resulted from femoral fracture. materials and methods: this is a cross-sectional study on all patients with femor...

External urban relations are commonly described as one of two types: hierarchical local hinterlands (central place theory) and networked non-local hinterworlds flow theory), referred to town-ness city-ness, respectively. This paper builds on develops these generic concepts make them specifically relevant today's corporate globalization. The central process is represented by multi-nodal global c...

Living systems use fuel-driven supramolecular polymers such as actin to control important cell functions. Fuel molecules like ATP are used to control when and where such polymers should assemble and disassemble. The cell supplies fresh ATP to the cytosol and removes waste products to sustain steady states. Artificial fuel-driven polymers have been developed recently, but keeping them in sustain...