Dracocephalum kotschyi Boiss. is a traditional medicine with antispasmodic activities. The objective of this research was to study antispasmodic activities of hydroalcoholic extract of D. kotschyi on rat isolated uterus contractions for comparison with isolated ileum. Hydroalcoholic extract was obtained from aerial part of D. kotschyi using percolation method. A portion of rat ileum or uterus w...

Colitis is an inflammatory disease of the intestine with unknown etiology involving multiple immune, genetic, and environmental factors. We were interested to examine the effect of total extract from Dracocephalum kotschyi (D. kotschyi) Boiss. on the experimental colitis. D. kotschyi hydroalcoholic extract (10, 20, and 40 mg/kg) or apigenin (5, 10, and 20 mg/kg) were administered orally 2 h pri...

Background and objectives: Tuberculosis (TB) is the major public health problem in the world. Each year there are 2-3 million deaths worldwide caused by TB. The increasing incidence of Multi Drug Resistance tuberculosis (MDR-TB) worldwide highlights the urgent need to search for new antituberculosis compounds. It has been reported that medicinal plant, Dracocephalum kotschyi, possesses some ant...

the volatile constituents of the aerial parts of varthemia. persica dc. var. persica, growing wild in iran, were investigated by gc-ms. sixty seven constituents were identified. ?-cadinene (9.7%), selin-11-en-4-?-ol (5.30%), germacrene d (4.9%), bicyclogermacrene (4.7%), ??muurolene (4.7%), ?-eudesmol (4.52%), ?-himachalen oxide (3.6%), ?-eudesmol (3.54%), ?-bourbonene (3.21%) were found to be ...

The volatile constituents of the aerial parts of Varthemia. persica DC. var. persica, growing wild in Iran, were investigated by GC-MS. Sixty seven constituents were identified. ?-Cadinene (9.7%), Selin-11-en-4-?-ol (5.30%), Germacrene D (4.9%), Bicyclogermacrene (4.7%), ??Muurolene (4.7%), ?-Eudesmol (4.52%), ?-Himachalen oxide (3.6%), ?-Eudesmol (3.54%), ?-Bourbonene (3.21%) were found to be...

The volatile constituents of the aerial parts of Varthemia. persica DC. var. persica, growing wild in Iran, were investigated by GC-MS. Sixty seven constituents were identified. ?-Cadinene (9.7%), Selin-11-en-4-?-ol (5.30%), Germacrene D (4.9%), Bicyclogermacrene (4.7%), ??Muurolene (4.7%), ?-Eudesmol (4.52%), ?-Himachalen oxide (3.6%), ?-Eudesmol (3.54%), ?-Bourbonene (3.21%) were found to be...

Nepetalactones are iridoid monoterpenes with a broad range of biological activities produced by plants in the Nepeta genus. However, none of the genes for nepetalactone biosynthesis have been discovered. Here we report the transcriptomes of two Nepeta species, each with distinctive profiles of nepetalactone stereoisomers. As a starting point for investigation of nepetalactone biosynthesis in Ne...