Introduction: Neoplasm metastasis is a multiple-step and multi-component involved pathogenesis causing large human mortality socioeconomic burden. Currently, anti-metastatic drugs are the widest therapeutic targets for clinical cancer trials. The most effective yet to be developed. Methods: Anti-metastatic evaluated by great variety of tumor models cutting-edge biotechnology. drug evaluation de...

 ABSTRACT Carcinoma of the cervix is a common neoplasm and accounts for a considerable number of cervical diseases that lead to death in developing countries. In these countries early detection and improved methods of treatment have resulted in comparatively better control of the cancer and long survival however, invasive and metastatic disease still occurs. The authors present the case report ...

Introduction:Oral Squamous Cell Carcinoma (OSCC) is an invasive neoplasm with a high prevalence. Matrix Metalloproteinase (MMP) has been thought to play an important role in both the invasion and metastasis of tumors. The aim of this study was to explore the significance of MMPs expression in clinical outcome of these patients. Materials:The most recognized data Bases such as PubMed, Google sc...

Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare glandular neoplasm that mimics benign lesions both clinically and histologically making it diagnostic challenge. Although indolent, ACC has potential for local regional distant metastasis even after surgical excision, there high recurrence rate. This report outlines case of PPACC reviews current therapeutic approaches.

abstract carcinoma of the cervix is a common neoplasm and accounts for a considerable number of cervical diseases that lead to death in developing countries. in these countries early detection and improved methods of treatment have resulted in comparatively better control of the cancer and long survival however, invasive and metastatic disease still occurs. the authors present the case report o...

Abstract Malignant melanoma is an aggressive neoplasm with a high tendency to metastasize. Gastrointestinal metastases, although described in the literature, are infrequent. We present case of 51-year-old male patient surficial spreading stage IIIc BRAF mutation who presented gallbladder outgrowth lesion, compatible polyp. A significant growth lesion was observed subsequent TC studies and lapar...

Merkel cell carcinoma is an extremely rare neuroendocrine neoplasm of the external auditory canal (EAC) skin, which requires wide excision and adjuvant radiation due to a high recurrence rate. In this report, we describe case arising from EAC was successfully treated with endoscopic excision. A 32-years-old female patient history papillary thyroid cancer diagnosed tumor incidentally. There eryt...

Carcinoma ex pleomorphic adenoma is an exceedingly rare neoplasm of the minor salivary gland. Prognostic parameters are recurrence, capsular invasion, and metastasis. We present a case of carcinoma ex pleomorphic adenoma with pulmonary metastasis to emphasize that patients treated for this condition should be investigated for distant metastasis.

Solid pseudopapillary neoplasm (SPN) of the pancreas is considered a low-malignant neoplasm with a good prognosis. However, 5% to 15% of patients with SPNs develop metastatic disease, most commonly in the liver. Metastatic hepatic malignancies that show pseudocystic features are rare. Here we describe the case of a middle-aged female with a cystic liver metastasis from SPN. To the best of our k...

The incidence of secondary testicular tumors ranges from 0.02 to 2.5% among autopsies in general. With the exception of leukemias and lymphomas, prostate cancer is the most common primary site. It is diagnosed in autopsies or incidentally, following therapeutic orchiectomies in more advanced stages of the disease. In the present report, we show a case of testicular metastasis derived from prost...