background: clinical and epidemiological variation was seen between the colon cancer (cc) and rectum cancer (rc). so, there is not so much data available about the epidemiological and clinicopathological differences and prognostic factors regarding to cc and cr in iran, we aimed to perform this study. methods: all cases of cc and rc referred to oncology and gastroenterology wards of taleghani g...

CONTEXT Oral squamous cell carcinoma (OSCC) is a malignant neoplasm of epithelial tissue origin. OSCC is traditionally graded into well, moderate and poorly differentiated. The assessment of cellular and nuclear features is very important in the histological grading of OSCC. AIMS To establish morphometric study as an important prognostic indicator of OSCC. SETTINGS AND DESIGN The present st...

48 fine needle aspiration biopsy (FNAB) samples from 25 breast cancer cases, originally used for cytodiagnosis were subjected to DNA cytometry. There were air dried smears stained with the MGG method, and samples stained with HE or PAP stain after 50% ethanol fixation and cytocentrifugation. Different sampling strategies were applied. Four methods were tested: method 1: cell groups measured, me...

Carcinoid tumor of the thymus is a rare neoplasm. It comprises a wide spectrum of lesions ranging from well-differentiated to poorly-differentiated neoplasms. We report a case of anterior mediastinal mass, which is proven to be an atypical thymic carcinoid tumor with a histopathological nature of intermediate-grade moderately-differentiated neuroendocrine carcinoma. We also present the patient’...

The present study aimed to assess whether patients with bladder urothelial tumours can be more objectively stratified into low- and high-risk groups for recurrence and progression using a 2-tired molecular grading scheme, than by subjective histopathological grading alone. Biopsy material from 45 consecutive patients with urothelial bladder neoplasias (2 papillary urothelial neoplasm of low mal...

Abstract Prostate cancer occures in male, especially over 65 year old. It develops usually in the peripheral zone, less commonly in central or transitional ones. The neoplasm screening bases on clinical digital rectal examination and serum level of prostate-specific antigen (PSA). Among patients with increase PSA concentration, transrectal ultrasound usually with multiple core biopsies is perfo...

OBJECTIVE To retrospectively compare the accuracy of the initial MRI (magnetic resonance imaging) report of referring radiologists and the second opinion report. MATERIAL AND METHODS MRI of 155 patients presenting with a soft tissue tumor (STT) in a single large community center were referred for inclusion in the Belgian Soft Tissue Neoplasm Registry (BSTNR). The initial report and the second...

In the 2016 version of WHO classification, bone marrow morphology is critical in the distinction between ET and pre-PMF. Reticulin-fiber grading becomes central: grade 1 or less is needed for ET. Furthermore, CALR assessment must be performed in all ET patients without JAK2 mutation. Some prognostic implications have been described for CALR mutations, i.e., a lower risk of thrombosis in ET. Abb...

Background: The genetic control of tumour progression presents the opportunity for bioinformatics and gene expression data to be used as a basis for tumour grading. The development of a genetic signature based on microarray data allows for the development of personalised chemotherapeutic regimes. Method: ONCOMINE was utilised to create a genetic signature for ovarian serous adenocarcinoma and t...

Intraoperative consultation; Smear cytology; Central nervous system neoplasm Smear cytology has been accepted as a suitable alternative to frozen section in intraoperative consultation of central nervous system tumours. Intraoperative smears from neurosurgical specimens permit rapid and accurate diagnosis. Grading of primary tumours may not be always possible on intraoperative smears, but their...