نتایج جستجو برای: negative sequence current nsc

تعداد نتایج: 1635815  

Journal: :Molecular pharmacology 2002
Libing Li Isao Matsuoka Yuichi Suzuki Yasuhide Watanabe Toshiyuki Ishibashi Keiko Yokoyama Yukio Maruyama Junko Kimura

Using the whole-cell voltage-clamp method, we investigated the effect of fluvastatin, a 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor, on lysophosphatidylcholine (LPC)-induced nonselective cation current (I(NSC)) in guinea pig cardiac ventricular myocytes. External LPC (3 to approximately 50 microM) induced I(NSC) in a dose-dependent manner with a lag. With fluvastatin (5 microM) in the ex...

Journal: :Cancer research 2005
Dehe Kong Eun Jung Park Andrew G Stephen Maura Calvani John H Cardellina Anne Monks Robert J Fisher Robert H Shoemaker Giovanni Melillo

The identification of small molecules that inhibit the sequence-specific binding of transcription factors to DNA is an attractive approach for regulation of gene expression. Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that controls genes involved in glycolysis, angiogenesis, migration, and invasion, all of which are important for tumor progression and metastasis. To identify in...

Journal: :JOURNAL OF MECHANICS OF CONTINUA AND MATHEMATICAL SCIENCES 2019

Journal: :Bioconjugate chemistry 2010
Reda Mhidia Aurélie Vallin Nathalie Ollivier Annick Blanpain Getao Shi Romain Christiano Ludger Johannes Oleg Melnyk

Peptide-protein conjugates are useful tools in different fields of research as, for instance, the development of vaccines and drugs or for studying biological mechanisms, to cite only few applications. N-Succinimidyl carbamate (NSC) chemistry has been scarcely used in this area. We show that unprotected peptides, featuring one lysine residue within their sequences, can be converted in good yiel...

1997
Gianna Bellè Eugenio Moggi

We introduce S2, a typed intermediate language for vectors, based on a 2level type-theory, which distinguishes between compile-time and run-time. The paper shows how S2 can be used to extract useful information from programs written in the Nested Sequence Calculus NSC, an idealized high-level parallel calculus for nested sequences. We study two translations from NSC to S2. The most interesting ...

Journal: :Indonesian Journal of Electrical Engineering and Computer Science 2022

The present Indian traction supply system’s complications (neutral sections of the catenary line and issues power quality) restrict growth railway transportation, particularly high-speed rail networks that are fast growing globally. neutral (NS) results in loss speed, momentum mechanical failures all threatening stable operation trains systems. In meantime, with quality such as negative sequenc...

2017
Yuewen Tang Pei Yu Lin Cheng

Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on NSC transplantation is a promising tool for the treatment of nervous system diseases. However, there are still many issues and controversies associated with the derivation and therapeutic application of these cells. In this review, we summarize the different sources of NSCs and their derivation methods, in...

Journal: :Acta neurobiologiae experimentalis 2010
Anna Jablonska Hanna Kozlowska Inga Markiewicz Krystyna Domanska-Janik Barbara Lukomska

Searching for a reliable source of alternative neural stem cells for experimental treatment of neurological disorders we have established neural stem cell line derived from human umbilical cord blood (HUCB-NSC) (Buzanska et al. 2006). These cells have been shown to differentiate along neuronal and glial lineages in the promoting in vitro conditions. In the current study we transplanted HUCB-NSC...

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