The rate of multiple births is substantially elevated in women who have had assisted reproduction treatment (ART; approximately 26%) compared to the general population ( approximately 1%), and these offspring are usually included in twin studies. Several studies have attempted to identify possible consequences of undergoing ART on the subsequent offspring. However, most studies have only includ...

BACKGROUND The risk of neural tube defects (NTDs) is significantly reduced by supplemental folic acid. NTD risk may be associated with impaired absorption of polyglutamyl folate, the primary form of naturally occurring food folate, and of folic acid in supplements or fortified food. Stable-isotope methods provide the specificity needed to test this hypothesis. OBJECTIVE We determined whether ...

Biologists often find themselves awestruck by the elegant perfection of living organisms. From the sophisticated ventilation system of a termite mound to the tensile strength of spider silk, nature has invariably selected the most effective designs through billions of years of relentless evolutionary pressures. From molecules to organisms, scientists and engineers have repeatedly been enthralle...

BACKGROUND Total folate intake includes naturally occurring food folate and folic acid from fortified foods and dietary supplements. Recent reports have focused on total folate intakes of persons aged > or =14 y. Information on total folate intakes of young children, however, is limited. OBJECTIVE The objective was to compute total folate and total folic acid intakes of US children aged 1-13 ...

Canine ehrlichiosis has emerged as one of the most clinically important tick-borne diseases affecting dogs. Eighty-five naturally infected dogs have been investigated, the most consistent clinical signs recorded were fever, emaciation and lymphoadenopathy, anemia, monocytosis, thrompocytopenia, hypoalbuminemia, elevation in liver enzymes and total bilirubin were the most remarkable changes asso...

more than half of all hydrocarbon reservoirs are naturally fractured reservoirs (nfrs), in which production forecasting is a complicated function of fluid flow in a fracture-matrix system. modelling of fluid flow in nfrs is challenging due to formation heterogeneity and anisotropy. stress sensitivity and depletion effect on already-complex reservoir permeability add to the sophistication. horiz...