Decidual natural killer cells accumulate at the fetal-maternal interface and play a key role in a successful pregnancy. However, their origin is still unknown. Do they derive from peripheral natural killer cells recruited in decidua or do they represent a distinct population that originates in situ? Here, we identified natural killer precursors in decidua and uterus of pregnant mice. These prec...

Recent results show that the repertoire of anti-MHC class 1-specific inhibitory receptors expressed by natural killer cells is influenced by self class 1 molecules in such a way as to minimize the number of cells with multiple self-reactive inhibitory receptors.

In normal human peripheral blood, cutaneous lymphocyte antigen is expressed by memory T cells, suggesting a specific tissue-homing population of T cells. In this study it is demonstrated that 6% of CD56 + natural killer cells in peripheral blood also express cutaneous lymphocyte antigen (CLA). It was also detected that most of the tumor cells in primary cutaneous nasal-type natural killer cell ...

Natural killer cells hunt rogue cancer in the bloodstream aided by increased fluid shear stress.