Synthetic calcium phosphates, e.g., hydroxyapatite (HAP) and tricalcium phosphate (TCP), are the most commonly used bone-graft materials due to their high chemical similarity natural hydroxyapatite—the inorganic component of bones. Calcium in form a free ion or bound complexes plays key role many biological functions, including bone regeneration. This paper explores possibility increasing Ca2+-...

Hydroxyapatite (HA) is the main natural mineral constituent of bones and a good alternative for biomedical applications because it osteoconductive, non-allergenic, non-carcinogenic, which ensures high biocompatibility. A commonly used method obtaining hydroxyapatite wet route, simple low-cost, produces only water as final residue, provides HA with crystallinity comparable to that bone tissue, f...

In order to begin to prepare a novel orthopedic implant that mimics the natural bone environment, the objective of this in vitro study was to synthesize nanocrystalline hydroxyapatite (NHA) and coat it on titanium (Ti) using molecular plasma deposition (MPD). NHA was synthesized through a wet chemical process followed by a hydrothermal treatment. NHA and micron sized hydroxyapatite (MHA) were p...

Bone tissue engineering (BTE) requires a sturdy biomaterial for scaffolds for restoration of large bone defects. Ideally, the scaffold should have a mechanical strength comparable to the natural bone in the implanted site. We show that adding cosolvent during the processing of our previously developed composite of hydroxyapatite-gelatin with a silane cross-linker can significantly affect its me...

Objective(s):   The production of nano-hydroxyapatite by two encapsulated bacterial strains was the goal of current research.  Materials and Methods:   Serratia marcscens ATCC 14756 and Pseudomonas aeruginosa PTCC 1570 were used by two methods including encapsulated form in 2% (w/v) alginate sodium powder and inoculated form (10%) in nutrient broth medium containing alginate sodium blank beads....

bone like hydroxyapatite (nhap) was synthesized via an in situ biomimetic process in presence of wheat starch. the effect of polymer concentration alteration on the final structure of nhap was investigated. formation of the nhap at room temperature was confirmed by x-ray diffraction (xrd) and fourier transform infrared spectroscopy (ft-ir). size and morphology of the nhap samples were character...