Assembling artificial collagenous tissues with structural, functional, and mechanical properties, which mimic natural tissues, is of vital importance for many tissue engineering applications. While the electromechanical properties of collagen are thought to play a role in, e.g., bone formation and remodeling, this functional property has not been adequately addressed in engineered tissues. Here...

In nature, some creatures can change their body shapes and surface colors simultaneously to respond the external environments, which greatly inspired researchers in development of color-tunable soft actuators. this work, we present a facile method prepare smart hydrogel actuator that bend bidirectionally color simultaneously, just like an octopus. The is fabricated by elastomer/hydrogel bilayer...

The repair of peripheral nerve injuries is still one of the most challenging tasks and concerns in neurosurgery. Effect of methylprednisolone-laden hydrogel loaded into a chitosan conduit on the functional recovery of peripheral nerve using a rat sciatic nerve regeneration model was assessed. A 10-mm sciatic nerve defect was bridged using a chitosan conduit (CHIT/CGP-Hydrogel) filled with CGP-h...

Wharton’s jelly mesenchymal stem cells (HWJMSCs) hold promise for myocardial regeneration, but optimal treatment regimen (preferably with a growth factor) is required to maximize functional benefits. The aim of this study was to explore the cardioprotective and angiogenesis effects of HWJMSCs combined with insulin-like growth factor-1 (IGF-1) in the treatment of acute myocardial infarction. Th...

Biomimetic reconstruction of tooth enamel is a significant topic of study in materials science and dentistry as a novel approach to the prevention, restoration, and treatment of defective enamel. We have developed a new amelogenin-containing chitosan hydrogel for enamel reconstruction that works through amelogenin supramolecular assembly, stabilizing Ca-P clusters and guiding their arrangement ...

Cesium radioactive isotopes (134Cs and 137Cs) are dangerous to human health due to their long half-life and high solubility in water. Nuclear experiments, wars, and nuclear plant accidents have been the main sources of Cs release into the environment. In recent years, several methods have been introduced for the elimination of Cs radioactive isotopes from contaminated wate...

Chitosan obtained by alkaline deacetylation of chitin is a non-toxic, biocompatible, and biodegradable natural polymer. Chitosan-based hydrogel polymeric beads have been extensively studied as microor nano-particulate carriers in the pharmaceutical and medical fields, where they have shown promise for drug delivery as a result of their controlled and sustained release properties, as well as bio...

Fiber bundles are present in many tissues throughout the body. In most cases, collagen subunits spontaneously self-assemble into a fibrilar structure that provides ductility to bone and constitutes the basis of muscle contraction. Translating these natural architectural features into a biomimetic scaffold still remains a great challenge. Here, a simple strategy is proposed to engineer biomimeti...

Agarose hydrogel, a solid electrolyte, was investigated voltammetrically in terms of transport properties and natural convection effects using ferrocenyl compound as redox probe. To confirm the diffusion solute on agarose interface, coefficients (D) ferrocenemethanol hydrogel were determined by cyclic voltammetry (CV) according to concentration hydrogel. While value D interface is smaller than ...