Treatment of Osteoarthritis of the Knee: Evidence-Based Guideline, 2nd Edition, is based on a systematic review of the current scientific and clinical research. This guideline contains 15 recommendations, replaces the 2008 AAOS clinical practice guideline, and was reevaluated earlier than the 5-year recommendation of the National Guideline Clearinghouse because of methodologic concerns regardin...

In contrast, the treatment of severe/complicated childhood malaria appears to be evolving. The 2005 IAP Guideline followed the National Malaria Programme and recommended quinine, suggesting artesunate/artemether as less preferred alternatives(3). In 2008, it was modified as quinine with tetracycline/doxycycline/clindamycin(4) in line with the WHO 2006 statement. The National Guideline 2009(2) s...

the international data have indicated a growing trend of alcohol use worldwide during recent years. although alcohol use is against cultural norms and religious law in iran, anecdotal reports from substance abuse treatment providers show that there is demand for alcohol treatment in the country. a recent national report also documented alcohol use disorders in iran. development and implementati...

The international data have indicated a growing trend of alcohol use worldwide during recent years. Although alcohol use is against cultural norms and religious law in Iran, anecdotal reports from substance abuse treatment providers show that there is demand for alcohol treatment in the country. A recent national report also documented alcohol use disorders in Iran. Development and implementati...

OBJECTIVES We conducted a comparative review of clinical practice guideline development handbooks. We aimed to identify the main guideline development tasks, assign weights to the importance of each task using expert opinions and identify the handbooks that provided a comprehensive coverage of the tasks. METHODS We systematically searched and included handbooks published (in English language)...

BACKGROUND Clinical practice guidelines are an important element of evidence-based practice. Considering an often complicated body of evidence can be problematic for guideline developers, who in the past may have resorted to using levels of evidence of individual studies as a quasi-indicator for the strength of a recommendation. This paper reports on the production and trial of a methodology an...

BACKGROUND There is international concern that conflicts of interest (COI) may bias clinical guideline development and render it untrustworthy. Guideline COI policies exist with the aim of reducing this bias but it is not known how such policies are interpreted and used by guideline producing organisations. This study sought to determine how conflicts of interest (COIs) are disclosed and manage...

To cite: Crowe BHA, Salt AT. Arch Dis Child Educ Pract Ed 2015;100:20–23. INFORMATION ABOUT THE CURRENT GUIDELINE In August 2013 the National Institute for Health and Care Excellence (NICE) collaborated with the Social Care Institute for Excellence (SCIE) to publish a guideline entitled ‘Autism: the management and support of children and young people on the autism spectrum’. It aims to summaris...

normal 0 false false false en-us x-none ar-sa pharmacists as one of health-care providers face ethical issues in terms of pharmaceutical care, relationship with patients and cooperation with the health-care team. other than pharmacy, there are pharmaceutical companies in various fields of manufacturing, importing or distributing that have their own ethical issues. therefore, pharmacy practice i...