نتایج جستجو برای: nasopharyngeal carcinoma npc
تعداد نتایج: 403499 فیلتر نتایج به سال:
Special AT rich sequence binding protein 1 (SATB1) play an important role in many cancers, but the role of SATB1 in nasopharyngeal carcinoma (NPC) is still not full understand. Immunofluorescence staining showed that SATB1 was mainly localized in the nuclei in CNE-2 cell. After successful down-regulation of SABT1 in NPC cell line CNE-2 by shRNA, compared to parental CNE-2 and control shRNA grou...
Cancer cells are characterized by a pathological manifestation of uncontrolled proliferation, which results in tumor formation. Therefore, it is necessary to improve understanding of the underlying mechanism of cell cycle control. Here, we report that miR‑150 is downregulated in nasopharyngeal carcinoma tissues and cells. Upregulation of miR‑150 suppresses nasopharyngeal carcinoma (NPC) cell pr...
Nasopharyngeal carcinoma (NPC) is one of commons tumours that found in Indonesia. NPC metastases on central nervous system (CNS) are rare case. Quick diagnose and proper therapy have greatly affected prognosis patient outcomes. Here we reported a case metastasis to epidural space 46-year-old woman with approach using 3 scoring systems specifically Abdurahman score, Tokuhasi Tomita score has goo...
Detection of nodal metastasis in the neck or adjacent structures is common in nasopharyngeal carcinoma (NPC) when there is frank primary disease. Intracranial extension without obvious nasopharyngeal disease is not common. Here, we discuss a patient with NPC that presented with extensive intracranial disease with subtle findings in the nasopharynx.
BACKGROUND Nasopharyngeal carcinoma (NPC) is a common malignancy in South-East Asia. NPC is characterized by distant metastasis and poor prognosis. The pathophysiological mechanism of nasopharyngeal carcinoma is unknown. This study aimed to identify the crucial miRNAs in nasopharyngeal carcinoma and their target genes, and to discover the potential mechanism of nasopharyngeal carcinoma developm...
BACKGROUND MicroRNAs have been considered as a kind of potential novel biomarker for cancer detection due to their remarkable stability in the blood and the characteristics of their expression profile in many diseases. METHODS We performed microarray-based serum miRNA profiling on the serum of twenty nasopharyngeal carcinoma patients at diagnosis along with 20 non-cancerous individuals as con...
Hepatocyte growth factor (HGF) and its receptor, c-Met, are associated with invasive tumor growth. This study sought to profile the expression of HGF and c-Met in nasopharyngeal carcinoma (NPC) tissue. Of 221 patients recruited between March 2010 and September 2013, 106 were diagnosed with nasopharyngeal carcinoma; the remaining 115 had nasal inflammation (nasopharyngeal mucositis) and were use...
Nasopharyngeal carcinoma (NPC) is one of the commonest head and neck malignancies in South East Asia. The tumor arises from epithelial layer nasopharynx, found most frequently at Fossa Rosenmuller (FOR). NPC can spread to its adjacent structures cause distant metastasis. However, occurrence dura metastasis uncommon despite being closely located. Consequently, a lesion may be misdiagnosed as men...
As an upstream activator for inducible nitric oxide synthase (iNOS), Mas has been reported to be upregulated in several cancers. However, its role in human nasopharyngeal carcinoma (NPC) is still unclear. In this study, we performed the immunohistochemistry to detect the expression of Mas and iNOS in 115 cases of NPC and 30 cases of normal nasopharyngeal tissues, and investigated the relationsh...
Introduction: Nasopharyngeal carcinoma (NPC) is commonly known as a radiosensitive tumor with the initial good response to radiation. Despite the improved outcome in loco regional control by the introduction of combining treatment, modern radiotherapy techniques and enhanced imaging studies, local recurrent after primary treatment with rate ranges from 15-58% in 5 years, stil...
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