Whereas skin protein synthesis can be measured with different approaches, no method potentially applicable in humans is available for measurement of skin protein breakdown. To that end, we measured mixed skin fractional protein breakdown (FBR) in a rat model by use of a stable isotope method (tracee release method) originally developed to measure muscle protein breakdown. Skin mixed protein and...

Background/Aim Surgeons often face with the problem when selecting a reconstructive method for nasal skin defects. The aim of this study was to determine functional and aesthetic character-istics of different reconstructive methods used for skin defects in different regions of the nose. Methods The study involved 44 patients with basocellular carcinoma in nasal area. The nasal skin was divide...

OBJECTIVES The aim of this study was to compare the usefulness of nasal smear eosinophilia with skin prick test for the diagnosis of allergic rhinitis and to determine the degree of correlation between the tests. PATIENTS AND METHODS Forty-one patients (16 males, 25 females; mean age 35.17; range 14 to 56 years) with a clinical history suggestive of nasal allergy and fifteen controls (7 males...

CPAP is the most studied form of noninvasive ventilation in neonates, and early investigations focused on the use of CPAP following surfactant administration, to minimize the need for invasive mechanical ventilation.1 Verder and colleagues demonstrated that a strategy of CPAP following brief intubation and surfactant administration (the INSURE technique: INtubation, SURfactant, Extubation) impr...

AIMS To determine the collective roles of stromelysin 1, neutrophil collagenase, and collagenase 3 in chondrocyte mediated cartilage proteoglycan and type II collagen degradation in tissue culture model systems. METHODS Bovine nasal cartilage explants were cultured with and without recombinant human interleukin 1 alpha (IL-1 alpha), recombinant human tumour necrosis factor alpha, or retinoic ...

The surgical treatment of circular skin defects localized on the nasal ala is always extremely challenging. Such lesions can be repaired by using full-thickness skin graft or skin flaps, normally with poor aesthetic outcomes. Skin grafts do not achieve satisfactory aesthetic results because of the unnatural look of the transplanted skin. If a skin flap is chosen, the choice of which one to empl...

OBJECTIVE A variety of nasal skin reconstruction methods are available to meet the esthetic patient's needs. In this article, we review some of modifications of these procedures and share our experience in reconstruction of different parts of the nasal skin following skin tumor ablation. PATIENTS AND METHODS From January 2010 to January 2014, 171 patients underwent nasal skin reconstruction a...

An epidemiologic investigation on Staphylococcus aureus (S. aureus) colonization in atopic skin diseases ZDV FRQGXFWHG DW øQ|Q 8QLYHUVLW\ 7XUJXW g]DO 0HGLFDO &HQWHU 7KH LQFLGHQFH RI XQDIIHFWHG VNLQ OHVLRQDO skin, and nasal positivity for S. aureus was examined in a total of 60 patients with atopic dermatitis and other atopic skin diseases. 50 healthy subjects were studied as controls. Normal s...

BACKGROUND Various techniques for lengthening short columellae have been used for bilateral cleft nose repair. However, previous methods have not yielded satisfactory results. We performed a full-thickness skin graft to lengthen short columellae during secondary cleft nose repair in adult patients. METHODS Ten bilateral cleft lip and nose patients underwent secondary cheiloplasty with open rh...

OBJECTIVES/HYPOTHESIS Skin irritation and ulceration beneath the tracheostomy tube or ties secondary to pressure and shearing forces on the skin frequently complicate pediatric tracheotomy in the immediate postoperative period. The aim of this study is to determine the effectiveness of Mepilex Ag dressings in reducing posttracheotomy wound complications. STUDY DESIGN Retrospective study. ME...