The objective of the present study was to formulate and evaluate nasal delivery system contains Ondansetron hydrochloride 4 mg/ml. Ondansetron hydrochloride loaded colloidal dispersion were prepared for nasal drug delivery using various polymers like β-cyclodextrin, hydroxyl propyl βcyclodextrin at different concentrations. The optimized formulation contains 0.02% benzalkonium chloride as a pre...

Intranasal administration is an attractive option for local and systemic delivery of many therapeutic agents. The nasal mucosa is – compared to other mucous membranes – easily accessible and provides a practical entrance portal for small and large molecules. Intranasal administration offers a rapid onset of therapeutic effects, no firstpass effect ,no gastrointestinal degradation or lung toxici...

Copyright © 2012 Frederick Furness Publishing 14 Nasal sprays that deliver active ingredients using droplets are well-established drug delivery vehicles, both for locally acting and systemic therapies. More recently, though, the pharmaceutical industry has started to turn its attention to delivering dry powders via the nasal route, a step that parallels the introduction of dry powder inhalers (...

Ayurveda is the ancient medical system in India that uses nasal therapy. During COVID -19 pandemic, ministry of AYUSH providedguidelines to boost immunity. The Nasya (nasal delivery) was one recommendations by immunity.Nasya has been still practice for various ailments like chronic rhinitis, headache, cervical spondylosis, Dyspnea, etc., but theknowledge about how works unclear.This review arti...

Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades. Intra-nasal administration of drugs offers an interesting alternative for achieving systemic therapeutic effects of drugs that are comparable to ...

BACKGROUND Over one hundred different pharmaceutical dosage forms have been recorded in literatures of Traditional Persian Medicine among which nasal forms are considerable. OBJECTIVES This study designed to derive the most often applied nasal dosage forms together with those brief clinical administrations. MATERIALS AND METHODS In the current study remaining pharmaceutical manuscripts of P...