BACKGROUND Growing evidence demonstrates the adverse effects of narcotics in inflammatory bowel disease (IBD). We sought to study the relationship between narcotic use, objective measures of disease activity, and other associated factors in hospitalized patients with IBD. METHODS We performed a retrospective cohort study of all adult IBD patients admitted to a general medical or surgical ward...

background: narcotic abuse by people accounts for major problems for developing countries such as iran. acute narcotic poisoning is one of the major mortality causes in these patients. the present study was designed to assess the clinical signs and symptoms of patients with narcotic poisoning at hospitals of yazd. methods: in this study, 500 patients with narcotic poisoning were assessed from n...

Search for a safe and effective analgesic is long and elusive. Buprenorphine was marketed as a potent and non-addictive narcotic drug. In recent years there have been various case reports highlighting its abuse potential. As the drug will be used more widely and particularly with its use in the detoxification of heroin dependence there is an eminent possibility of its abuse at larger scale in f...

Self administered questionnaires completed by 69 out of 100 consecutive drug addicts attending two drug dependence clinics suggested that some private general practitioners were easily persuaded to prescribe controlled drugs. These drugs were usually methadone, dipipanone-cyclizine (Diconal), and methylphenidate (Ritalin). Numbers of new narcotic addicts notified to the Home Office confirmed th...

Narcotics affect adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] in two opposing ways, both mediated by the opiate receptor. The first process is the readily reversible inhibition of the enzyme by narcotics; the second is a compensatory increase in enzyme activity which is delayed in onset and relatively stable. Late positive regulation of the enzyme counteracts the inhibito...

Background Pain, although invariably present after surgical procedures, is not always well controlled. Medications from different analgesic groups are often used to control post-operative pain. Recently, attention has turned towards the optimization of non-opioid analgesics including NSAIDS and acetaminophen. After gynaecologic laparoscopy up to 80% of patients may require opioid analgesia. How...

It may sound a little nutty, but your friends are partially correct. Nutmeg, a spice commonly used to flavor lattes, sweets, and other foods has also been reported to produce a high that is similar to the one obtained with marijuana. Originating from the Myristica fragans tree in Indonesia, the seed is now grown and used globally, mostly for cooking but sometimes as a narcotic. However, for the...