The present study discusses evaluation of pullulan-functionalized doxorubicin nanoparticles for asialoglycoprotein receptor-mediated uptake in the Hep G2 cell line. Doxorubicin hydrochloride (DOX) nanoparticles using polymers of different hydrophobic character, polyethylene sebacate (hydrophobic) and poly (lactic-co-glycolic acid) (intermediate hydrophobicity) with high entrapment efficiency an...

In this study, we have synthesized the gold nanoparticles by using Hibiscus rosa-sinensis, a medicinal plant. The gold nanoparticles were synthesized rapidly by the involvement of microwave heating. By changing of plant extract concentration, gold solution concentration, microwave heating time and power of microwave heating the optimized condition was identified. The surface Plasmon resonance f...

in the current research, polyvinylchloride based mixed matrix heterogeneous anion exchange membranes were prepared by a solution casting technique. titanium dioxide nanoparticles were also utilized as inorganic filler additive in the membrane fabrication. the effect of tio2 nanoparticles concentration in the casting solution on the membrane physico-chemical properties was studied. membrane wate...

Background: Magnetite (Fe3O4) nanoparticles are currently one of the important and acceptable magnetic nanoparticles for biomedical applications. To use magnetite nanoparticles for bacteria cell separation, the surface of nanoparticles would be modified for immobilizing of nanoparticles on the surface of bacteria. Functionalization of magnetite nanoparticles is performed by different s...

Gold nanoparticles are promising as a kind of novel radiosensitizer in radiotherapy. If gold nanoparticles are shown to have good irradiation stability and biocompatibility, they would play an important role in radiotherapy. In this work, we investigated irradiation effects of gold nanoparticles under 2-10 kR gamma irradiation and cytotoxicity of gold nanoparticles with human K562 cells by usin...

The dependence of nanoparticle concentration on the conformation of bovine serum albumin has been studied. A very small but consistent enhancement in the tryptophan emission is observed in the presence of sub-picomolar concentration of gold nanoparticles. At this concentration, the bovine serum albumin unfolding profile in presence and absence of nanoparticles are quite similar and the protein ...

in this research controlled coating of magnetite (fe3o4) nanoparticles with sio2 was investigated. the fe3o4 nanoparticles were synthesized via chemical co-precipitation and then coated by silica according to stober method. effects of tetra ethyl ortho silicate (teos) concentration and ethanol to teos on the coating thickness were investigated. x-ray powder diffraction, fourier transform infrar...

We prepared amphotericin B (AmB) nanoparticles through liquid antisolvent precipitation (LAP) and by freeze-drying to improve the solubility of AmB for oral administration. The LAP was optimized through a single-factor experiment. We determined the effects of surfactants and their concentration, the stirring time, the precipitation temperature, the stirring intensity, the drug concentration and...