Combinations of three simple techniques were utilized to gradually form zirconia nanoneedles from zirconium nanograins. First, a physical vapor deposition magnetron sputtering technique was used to deposit pure zirconium nanograins on top of a substrate. Second, an anodic oxidation was applied to fabricate zirconia nanotubular arrays. Finally, heat treatment was used at different annealing temp...

An important aspect of orthopedic implant integration is the enhancement of functional activity of osteoblasts at the tissue-implant interface without any fibrous tissue intervention. Nanostructured implant surfaces are known to enhance osteoblast activity. Previously, we have reported a simple hydrothermal method for the fabrication of non-periodic nanostructures (nanoscaffold, nanoleaves and ...

Since the hydrophobic group is always essential to the synthesis of the drug-loaded nanoparticles, a majority of the methods rely heavily on organic solvent, which may not be completely removed and might be a potential threat to the patients. In this study, we completely "green" synthesized 10-hydroxycamptothecine (HCPT) loaded, folate (FA)-modified nanoneedles (HFNDs) for highly efficient canc...

We have successfully and reproducibly synthesized a variety of novel vanadium dioxide (VO2) nanostructures, including metastable monoclinic VO2(B) nanoneedles and nanocorals, orthorhombic VO2(O) nanoparticles, and monoclinic VO2(M) nanofacets by manipulating the aging time of a facile sol-gel approach and the subsequent postannealing conditions. We envision that this previously unreported highl...

The control of the optical properties ZnO nanostructured thin films by using different dopant elements paves way for development potential materials photonic and optoelectronic applications. In this work manganese (Mn) doped were fabricated rapid thermal evaporation method on a glass substrate having same Mn content level ~10% annealed at temperatures. XRD analysis showed that layers have hexag...

We present a dense needle array with sharp nano-tips for intracellular gene and drug delivery, with the ultimate goal of gene correction in a high throughput manner. The nanoneedles are fabricated using isotropic dry etching of silicon, followed by anisotropic dry etching and thermal-oxidation-based tip sharpening. The nanoneedle density is as large as 10 needles per square centimeter. In-vitro...