BACKGROUND Titanium is an inert metal that does not induce osteogenesis and has no antibacterial properties; it is proposed that hydroxyapatite coating can enhance its bioactivity, while zinc can contribute to antibacterial properties and improve osseointegration. AIMS A nano-sized hydroxyapatite-zinc coating was deposited on commercially pure titanium using an electro-chemical process, in or...

in this work, we report high biological performance of silicon substituted nano hydroxyapatite (nha) prepared by immersion of calcium phosphate and sodium silicate as precursors in simulated body fluid (sbf) solution for 24, 36, 48 and 72 hrs at 37°c. characterization and chemical analysis of the synthesized powders were performed by fourier transform, infrared spectroscopy (ft-ir), x-ray powde...

The purpose of this study is to synthesize nano-grained Calcium Hydroxyapatite (HAp) through slip casting technique. For this, hydroxyapatite powders were synthesized using two methods, wet chemical method and Ammoniacal method. The as-prepared powders and calcined powders were characterized using XRD, FTIR, to study the phases of the powders. The hydroxyapatite powder calcined at 1000°C for 2h...

AIM The aim of the study was to comparatively analyze the in vitro cell adhesion between nano coated titanium dioxide, and calcium hydroxyapatite (HA) coated titanium samples. MATERIALS AND METHODS Nano coated titanium dioxide, and calcium HA were coated onto the titanium samples by drop casting with NAFION membrane and cell culture was done by seeding human osteoblastic sarcoma cells on the ...

BACKGROUND Nano-hydroxyapatite (nHA) is a potential ideal biomaterial for bone regeneration. However, studies have yet to characterize the behavior of human osteoblasts derived from alveolar bone on nHA. Thus, the aim of the present study was to evaluate the influence of nHA on the adhesion, proliferation and differentiation of these alveolar bone-derived cells. METHODS Primary human alveolar...

OBJECTIVE This clinical study aimed to evaluate effectiveness of a commercially available toothpaste containing potassium nitrate, sodium monoflurophosphate, and nano-hydroxyapatite as well as antioxidants phloretin, ferulic acid and silymarin in reducing dental hypersensitivity in adults. METHODS The clinical trial enrolled patients with a history of dentin hypersensitivity. A test toothpast...

In this study, we investigated the effects of temozolomide (TMZ)/Poly (lactide-co-glycolide)(PLGA)/nano-hydroxyapatite microspheres on the behavior of U87 glioma cells. The microspheres were fabricated by the "Solid/Water/Oil" method, and they were characterized by using X-Ray diffraction, scanning electron microscopy and differential scanning calorimetry. The proliferation, apoptosis and invas...

Acceleration of bone healing has always been a major challenge in orthopedic surgery, the aim of this study was an evaluation of the biological effects of zirconia-stabilized yttria on bone healing, using an in vivo model. Nano-hydroxyapatite powder with zirconia-stabilized yttria were inserted in rabbit tibia and then histologically analyzed and compared with non-treated controls so thirty six...