Histone H2AX phosphorylation is an early signalling event triggered by DNA double-strand breaks (DSBs). To elucidate the elementary units of phospho-H2AX-labelled chromatin, we integrate super-resolution microscopy of phospho-H2AX during DNA repair in human cells with genome-wide sequencing analyses. Here we identify phospho-H2AX chromatin domains in the nanometre range with median length of ∼7...

We propose a method of optical data storage that exploits the small dimensions of metallic nano-particles and/or nano-structures to achieve high storage densities. The resonant behavior of these particles (both individually and in small clusters) in the presence of ultraviolet, visible, and near-infrared light may be used to retrieve pre-recorded information by far-field spectroscopic optical d...

The phase stability and electronic structure of alpha- LiBH(4)-derived nanostructures and possible low energy surfaces of thin films have been investigated using the ab initio projected augmented plane wave method. Structural optimizations based on total energy calculations predicted that, for the alpha- LiBH(4) phase, the (010) surface is the most stable of the possible low-energy surfaces. Th...

Chemically functionalized and nanostructured materials, which mimic the features of the natural extracellular matrix, provide a tool to organize cell surface receptors into nanoscale clusters and manipulate cell functions. However, the existing materials are mainly based on static structures. Herein, we developed a DNA based structure-switchable and multivalent material that acts as a 'nano-spr...

Abstract In the study of plastic flow and mechanical features zinc subjected to severe deformation at low temperature through KOBO extrusion method, three techniques micro nanostructure identification have been used (TEM, STEM, HAADF). It was shown that pattern long trails—a typical element microstructure after deformation, results from strain fields densely spaced nano-dimensional clusters poi...

0.1016/j.nanoen.2 lsevier Ltd. All rig thor. [email protected] Abstract The reversibility and stability of Li2S electrode can be improved by carbon coating on nano sized Li2S. However, how to uniformly coat a dense layer of carbon on nano sized Li2S is still challenge so far. Here, we utilized a novel flowable ionic liquid (1-Ethyl-3-methylimidazolium dicyanamide) as a carbon precursor to uniformly...

In this study, we used a 30 keV argon cluster ion beam bombardment to investigate the dynamic processes during nano-ripple formation on gold surfaces. Atomic force microscope analysis shows that the gold surface has maximum roughness at an incident angle of 60° from the surface normal; moreover, at this angle, and for an applied fluence of 3 × 1016 clusters/cm², the aspect ratio of the nano-rip...

A fully physically-based thermodynamic and kinetic model of the β ↔ δ phase transformation in energetic crystal HMX crystal embedded in polymeric binder is developed. It is based on a new nucleation mechanism via melt mediated nano-cluster transformation and the recently formulated growth mechanism via internal stress-induced virtual melting. During the nucleation, nano-sized clusters of β phas...

A self-consistent environment-dependent tight binding method is used to examine electron emission-related properties of hydrogen passivated nano-diamond (ND) particles. For sizes larger than 2.5 nm particle bandgap was found to be equal to the bandgap of bulk diamond. Coulomb potential distributions and electron affinities of clusters were found to be insensitive to the particle size if it exce...